KRT6B and TUBGCP4

Data Source:
BioGRID (two hybrid)

		KRT6B	TUBGCP4
Description		keratin 6B	tubulin gamma complex associated protein 4
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Keratin Filament Extracellular Exosome	Spindle Pole Equatorial Microtubule Organizing Center Gamma-tubulin Complex Centrosome Cytosol Microtubule Gamma-tubulin Ring Complex Microtubule Cytoskeleton Membrane Recycling Endosome
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding	Structural Constituent Of Cytoskeleton Protein Binding Gamma-tubulin Binding Microtubule Minus-end Binding
	Biological Process	Cytoskeleton Organization Ectoderm Development Keratinization Cornification	Mitotic Cell Cycle Microtubule Nucleation Cytoplasmic Microtubule Organization Spindle Assembly Meiotic Cell Cycle Protein-containing Complex Assembly
Pathways		Keratinization Formation of the cornified envelope	Recruitment of mitotic centrosome proteins and complexes Recruitment of NuMA to mitotic centrosomes
Drugs
Diseases		Pachyonychia congenita, including: Jadassohn-Lewandowsky syndrome; Jackson-Lawler syndrome ; Steatocystoma multiplex
GWAS			Glycine levels ( 30837465) HDL cholesterol ( 30275531) Triglycerides ( 30275531)
Interacting Genes		25 interacting genes: GOLGA2 KDM1A KIFC3 KRT13 KRT15 KRT19 KRT25 KRT27 KRT28 KRT31 KRT33B KRT35 KRT37 KRT38 KRT39 KRT40 LINC00839 NDC80 NUP62 OIP5 SMARCB1 TEX11 TFIP11 TRIM54 TUBGCP4	32 interacting genes: ADAMTSL4 AP2B1 CBY2 CCDC85B CHIC2 DGCR6 EFHC2 FBF1 FDXACB1 GFAP GLYCTK GOLGA2 KCTD17 KRT15 KRT18 KRT4 KRT6B LZTR1 MAD1L1 NUDT3 PAK5 PHKA1 RNF146 RPRD1B SDSL STN1 TRIM27 TRIM55 TRIM63 TUBG1 USHBP1 VIM
Entrez ID		3854	27229
HPRD ID		01012	10616
Ensembl ID		ENSG00000185479	ENSG00000137822
Uniprot IDs		P04259	Q9UGJ1
PDB IDs			3RIP 6V69 6V6S
Enriched GO Terms of Interacting Partners?
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