TUBGCP4 and TUBG1

Data Source:
HPRD (in vivo)

		TUBGCP4	TUBG1
Description		tubulin gamma complex associated protein 4	tubulin gamma 1
Image
GO Annotations	Cellular Component	Spindle Pole Equatorial Microtubule Organizing Center Gamma-tubulin Complex Centrosome Cytosol Microtubule Gamma-tubulin Ring Complex Microtubule Cytoskeleton Membrane Recycling Endosome	Condensed Nuclear Chromosome Gamma-tubulin Complex Nucleus Cytoplasm Centrosome Spindle Polar Microtubule Cytosol Microtubule Recycling Endosome Mitotic Spindle Microtubule
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Gamma-tubulin Binding Microtubule Minus-end Binding	GTPase Activity Structural Constituent Of Cytoskeleton Protein Binding GTP Binding Identical Protein Binding
	Biological Process	Mitotic Cell Cycle Microtubule Nucleation Cytoplasmic Microtubule Organization Spindle Assembly Meiotic Cell Cycle Protein-containing Complex Assembly	Mitotic Sister Chromatid Segregation G2/M Transition Of Mitotic Cell Cycle Meiotic Spindle Organization Microtubule Cytoskeleton Organization Mitotic Cell Cycle Microtubule Nucleation Mitotic Spindle Organization Regulation Of G2/M Transition Of Mitotic Cell Cycle Cytoplasmic Microtubule Organization Ciliary Basal Body-plasma Membrane Docking
Pathways		Recruitment of mitotic centrosome proteins and complexes Recruitment of NuMA to mitotic centrosomes	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs			Vinblastine
Diseases
GWAS		Glycine levels ( 30837465) HDL cholesterol ( 30275531) Triglycerides ( 30275531)	Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549)
Interacting Genes		32 interacting genes: ADAMTSL4 AP2B1 CBY2 CCDC85B CHIC2 DGCR6 EFHC2 FBF1 FDXACB1 GFAP GLYCTK GOLGA2 KCTD17 KRT15 KRT18 KRT4 KRT6B LZTR1 MAD1L1 NUDT3 PAK5 PHKA1 RNF146 RPRD1B SDSL STN1 TRIM27 TRIM55 TRIM63 TUBG1 USHBP1 VIM	28 interacting genes: APP BRCA1 CENPJ CNTN2 CUL4A DDX41 IKBKG KIF14 KRT18 KRT19 MARK4 NAPG NDE1 PCNT PIK3R1 PLK1 PXN RACGAP1 RACK1 RASSF1 RNF19A RPGR SPATC1 TUBA1B TUBA3C TUBB4B TUBGCP3 TUBGCP4
Entrez ID		27229	7283
HPRD ID		10616	01853
Ensembl ID		ENSG00000137822	ENSG00000131462
Uniprot IDs		Q9UGJ1	P23258
PDB IDs		3RIP 6V69 6V6S	1Z5V 1Z5W 3CB2 6V5V 6V6S
Enriched GO Terms of Interacting Partners?
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