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KRTAP5-9 and P4HB
Data Source:
BioGRID
(two hybrid)
KRTAP5-9
P4HB
Description
keratin associated protein 5-9
prolyl 4-hydroxylase subunit beta
Image
No pdb structure
GO Annotations
Cellular Component
Cytosol
Keratin Filament
Extracellular Region
Endoplasmic Reticulum
Endoplasmic Reticulum Lumen
Endoplasmic Reticulum-Golgi Intermediate Compartment
Cytosol
Cytoskeleton
Focal Adhesion
External Side Of Plasma Membrane
Procollagen-proline 4-dioxygenase Complex
Lamellipodium
Protein-containing Complex
Melanosome
Extracellular Exosome
Molecular Function
Protein Binding
Identical Protein Binding
RNA Binding
Protein Disulfide Isomerase Activity
Actin Binding
Procollagen-proline 4-dioxygenase Activity
Integrin Binding
Protein Binding
Peptide Disulfide Oxidoreductase Activity
Thiol Oxidase Activity
Protein Heterodimerization Activity
Biological Process
Epidermis Development
Keratinization
Protein Folding
Protein Phosphopantetheinylation
Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline
Chylomicron Assembly
Very-low-density Lipoprotein Particle Assembly
Protein Folding In Endoplasmic Reticulum
Response To Endoplasmic Reticulum Stress
Interleukin-12-mediated Signaling Pathway
Interleukin-23-mediated Signaling Pathway
Post-translational Protein Modification
Cellular Protein Metabolic Process
Positive Regulation Of Cell Adhesion
Positive Regulation Of Viral Entry Into Host Cell
Cellular Response To Hypoxia
Positive Regulation Of Substrate Adhesion-dependent Cell Spreading
Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Pathways
Keratinization
Collagen biosynthesis and modifying enzymes
Detoxification of Reactive Oxygen Species
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Hedgehog ligand biogenesis
VLDL assembly
Post-translational protein phosphorylation
Chylomicron assembly
Interleukin-12 signaling
Interleukin-23 signaling
Drugs
Zinc
Ribostamycin
Copper
Artenimol
Zinc acetate
Zinc chloride
Zinc sulfate, unspecified form
Diseases
GWAS
Interacting Genes
196 interacting genes:
ABHD17A
ADAM12
ADAMTSL4
ADAMTSL5
ALDH3B1
ALPP
ATG9A
BEX2
BMP7
C10orf62
C11orf87
CATSPER1
CHIC2
CHRD
CHRNG
CKS1B
CNNM3
COL8A1
COMT
CRCT1
CREB5
CRH
CRY2
CTNNBIP1
CTSZ
CXCL16
CYSRT1
DCDC2
DHRS1
DMRT3
DNASE1L3
DOCK2
EMC7
ENKD1
ENPP7
FAH
FAM124B
FAM161A
FAM74A4
FAM76B
FLT3LG
GGN
GLP1R
GLRX3
GNE
GRN
GSC2
HEY2
HHEX
HLCS
HOXA1
HOXB9
HPCAL1
HSD3B7
HSPD1
IGFBP6
JOSD1
KLHL38
KLK8
KPRP
KRTAP1-3
KRTAP10-1
KRTAP10-10
KRTAP10-11
KRTAP10-3
KRTAP10-5
KRTAP10-6
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP11-1
KRTAP12-1
KRTAP12-2
KRTAP12-3
KRTAP2-3
KRTAP2-4
KRTAP4-11
KRTAP4-12
KRTAP4-2
KRTAP4-4
KRTAP4-5
KRTAP5-11
KRTAP5-2
KRTAP5-3
KRTAP5-4
KRTAP5-6
KRTAP9-2
KRTAP9-3
KRTAP9-4
KRTAP9-8
LCE1A
LCE1B
LCE1C
LCE1D
LCE1E
LCE1F
LCE2A
LCE2B
LCE2C
LCE2D
LCE3A
LCE3B
LCE3C
LCE3D
LCE3E
LCE4A
LCE5A
LELP1
LINGO1
LNX1
LY6H
MAPKBP1
MEOX2
MOBP
MT1M
NAXD
NBPF19
NCLN
NECTIN2
NECTIN3
NKD1
NLK
NMU
NOTCH2NLA
NPBWR2
NPDC1
NR4A3
NTAQ1
NTM
NTN4
NUFIP2
OTX1
P2RX4
P2RY6
P4HB
PCSK5
PDE9A
PFKL
PGAP6
PGLS
PHLDA1
PIN1
POM121L8P
POTEB3
POU4F2
PRKAB2
PSMA1
PTPMT1
RAMP3
RASD1
RGS20
RNF111
SCARB1
SCNM1
SDC3
SDCBP
SEMA3B
SHFL
SLC13A5
SLC15A3
SLC22A23
SLC25A10
SMCP
SPATA3
SPATC1L
SPG7
SPINK2
SPRY1
SPRY2
TBC1D10C
TBC1D16
TCEA2
TCEANC
TGM1
TOMM22
TRARG1
TYRO3
UBE2I
UXT
VWC2
WNT11
YIPF3
ZBTB24
ZFYVE21
ZNF124
ZNF266
ZNF408
ZNF414
ZNF417
ZNF439
ZNF440
ZNF581
ZNF587
ZNF655
ZNF696
ZNF837
49 interacting genes:
CD1D
CHCHD2
CNNM3
COL10A1
COL1A1
COL1A2
CSNK2A2
CST2
EIF2S1
ENO1
ERO1A
ERO1B
ESR1
FAM71C
FEZ1
FZD10
GRN
HNRNPD
ITGB3
KLHL42
KRTAP12-3
KRTAP13-2
KRTAP4-11
KRTAP5-9
KRTAP6-3
KRTAP9-8
LCE1B
LCE2D
LCE4A
LCN2
LGALS9
LINC00839
LRFN4
NECTIN2
NOL4
NTM
ODF1
P4HA2
P4HA3
PLCXD3
PRNP
PTN
SUMO2
TG
TGFB1
UBQLN1
VWF
YWHAG
ZNF69
Entrez ID
3846
5034
HPRD ID
01008
07181
Ensembl ID
ENSG00000254997
ENSG00000185624
Uniprot IDs
P26371
A0A024R8S5
P07237
PDB IDs
1BJX
1MEK
1X5C
2BJX
2K18
3BJ5
3UEM
4EKZ
4EL1
4JU5
6I7S
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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