P4HB and KRTAP13-2

Data Source:
BioGRID (two hybrid)

		P4HB	KRTAP13-2
Description		prolyl 4-hydroxylase subunit beta	keratin associated protein 13-2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum-Golgi Intermediate Compartment Cytosol Cytoskeleton Focal Adhesion External Side Of Plasma Membrane Procollagen-proline 4-dioxygenase Complex Lamellipodium Protein-containing Complex Melanosome Extracellular Exosome	Cytosol Intermediate Filament
	Molecular Function	RNA Binding Protein Disulfide Isomerase Activity Actin Binding Procollagen-proline 4-dioxygenase Activity Integrin Binding Protein Binding Peptide Disulfide Oxidoreductase Activity Thiol Oxidase Activity Protein Heterodimerization Activity	Protein Binding
	Biological Process	Protein Folding Protein Phosphopantetheinylation Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline Chylomicron Assembly Very-low-density Lipoprotein Particle Assembly Protein Folding In Endoplasmic Reticulum Response To Endoplasmic Reticulum Stress Interleukin-12-mediated Signaling Pathway Interleukin-23-mediated Signaling Pathway Post-translational Protein Modification Cellular Protein Metabolic Process Positive Regulation Of Cell Adhesion Positive Regulation Of Viral Entry Into Host Cell Cellular Response To Hypoxia Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway	Keratinization
Pathways		Collagen biosynthesis and modifying enzymes Detoxification of Reactive Oxygen Species Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Hedgehog ligand biogenesis VLDL assembly Post-translational protein phosphorylation Chylomicron assembly Interleukin-12 signaling Interleukin-23 signaling	Keratinization
Drugs		Zinc Ribostamycin Copper Artenimol Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS
Interacting Genes		49 interacting genes: CD1D CHCHD2 CNNM3 COL10A1 COL1A1 COL1A2 CSNK2A2 CST2 EIF2S1 ENO1 ERO1A ERO1B ESR1 FAM71C FEZ1 FZD10 GRN HNRNPD ITGB3 KLHL42 KRTAP12-3 KRTAP13-2 KRTAP4-11 KRTAP5-9 KRTAP6-3 KRTAP9-8 LCE1B LCE2D LCE4A LCN2 LGALS9 LINC00839 LRFN4 NECTIN2 NOL4 NTM ODF1 P4HA2 P4HA3 PLCXD3 PRNP PTN SUMO2 TG TGFB1 UBQLN1 VWF YWHAG ZNF69	80 interacting genes: ANAPC11 ANXA11 BCL6 C11orf1 C22orf39 CBFA2T2 CCDC125 CCDC24 CCDC57 CCNK CRYBA1 CSKMT CYSRT1 ENKD1 EPDR1 ETFDH FANCL FBXO17 FCHO1 GATA3 GEMIN4 GNE GPS2 GRN HNRNPH1 HOXA1 HR KCTD9 KLHL38 KPRP KRT3 KRTAP1-1 KRTAP10-5 KRTAP11-1 KRTAP12-2 KRTAP12-3 KRTAP15-1 KRTAP26-1 KRTAP3-1 KRTAP3-3 KRTAP4-4 KRTAP4-5 KRTAP9-2 MAGOHB MEOX2 MGAT5B NBPF19 NEK8 NHLRC4 NOTCH2NLA OIP5 OTX1 P4HB PATZ1 PHETA1 PITX1 POU2AF1 PPP1R32 RECK RHOXF2 SLC25A18 SLIT1 SMUG1 SNRPC SPEF1 SSC4D STK16 TCAF1 TEX37 TLE5 TNS2 TRAPPC6A TRIM68 TSPYL6 TSSK3 UNC5CL VGLL3 VWC2 YPEL3 ZIC1
Entrez ID		5034	337959
HPRD ID		07181	11201
Ensembl ID		ENSG00000185624	ENSG00000182816
Uniprot IDs		A0A024R8S5 P07237	Q52LG2
PDB IDs		1BJX 1MEK 1X5C 2BJX 2K18 3BJ5 3UEM 4EKZ 4EL1 4JU5 6I7S
Enriched GO Terms of Interacting Partners?
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