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NUP98 and SEC13
Data Source:
BioGRID
(affinity chromatography technology)
HPRD
(in vitro, two hybrid)
NUP98
SEC13
Description
nucleoporin 98 and 96 precursor
SEC13 homolog, nuclear pore and COPII coat complex component
Image
GO Annotations
Cellular Component
Kinetochore
Nuclear Envelope
Nuclear Pore
Nucleoplasm
Cytosol
Nuclear Body
Nuclear Pore Outer Ring
Nuclear Membrane
Nuclear Periphery
Nuclear Inclusion Body
Intracellular Membrane-bounded Organelle
Host Cell
Nuclear Pore Nuclear Basket
Ribonucleoprotein Complex
Golgi Membrane
Kinetochore
Nuclear Envelope
Nucleoplasm
Lysosomal Membrane
Endoplasmic Reticulum Membrane
Cytosol
ER To Golgi Transport Vesicle Membrane
COPII Vesicle Coat
Nuclear Pore Outer Ring
Intracellular Membrane-bounded Organelle
Host Cell
GATOR2 Complex
Extracellular Exosome
Molecular Function
Transcription Coactivator Activity
MRNA Binding
Transporter Activity
Protein Binding
Nuclear Localization Sequence Binding
Serine-type Peptidase Activity
Structural Constituent Of Nuclear Pore
Promoter-specific Chromatin Binding
Structural Molecule Activity
Protein Binding
Identical Protein Binding
Biological Process
Regulation Of Glycolytic Process
MRNA Export From Nucleus
TRNA Export From Nucleus
Proteolysis
Protein Import Into Nucleus
Nucleocytoplasmic Transport
Nuclear Pore Organization
Viral Process
Protein Sumoylation
Viral Transcription
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of MRNA Splicing, Via Spliceosome
Nuclear Pore Complex Assembly
Regulation Of Gene Silencing By MiRNA
Intracellular Transport Of Virus
Regulation Of Cellular Response To Heat
Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I
Regulation Of Glycolytic Process
MRNA Export From Nucleus
TRNA Export From Nucleus
Protein Import Into Nucleus
Intracellular Protein Transport
Viral Process
Viral Transcription
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Positive Regulation Of TOR Signaling
Protein Exit From Endoplasmic Reticulum
COPII Vesicle Coating
Regulation Of Gene Silencing By MiRNA
Intracellular Transport Of Virus
COPII-coated Vesicle Cargo Loading
COPII-coated Vesicle Budding
Regulation Of Cellular Response To Heat
Positive Regulation Of TORC1 Signaling
Pathways
ISG15 antiviral mechanism
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Transport of the SLBP independent Mature mRNA
Transport of the SLBP Dependant Mature mRNA
Transport of Mature mRNA Derived from an Intronless Transcript
Transport of Mature mRNA derived from an Intron-Containing Transcript
Rev-mediated nuclear export of HIV RNA
Transport of Ribonucleoproteins into the Host Nucleus
NS1 Mediated Effects on Host Pathways
Viral Messenger RNA Synthesis
NEP/NS2 Interacts with the Cellular Export Machinery
Regulation of Glucokinase by Glucokinase Regulatory Protein
Nuclear import of Rev protein
Vpr-mediated nuclear import of PICs
snRNP Assembly
COPII-mediated vesicle transport
MHC class II antigen presentation
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
SUMOylation of DNA damage response and repair proteins
SUMOylation of ubiquitinylation proteins
Nuclear Pore Complex (NPC) Disassembly
Regulation of HSF1-mediated heat shock response
SUMOylation of SUMOylation proteins
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA replication proteins
Transcriptional regulation by small RNAs
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)
RHO GTPases Activate Formins
tRNA processing in the nucleus
Mitotic Prometaphase
HCMV Early Events
HCMV Late Events
Postmitotic nuclear pore complex (NPC) reformation
Postmitotic nuclear pore complex (NPC) reformation
Amino acids regulate mTORC1
EML4 and NUDC in mitotic spindle formation
Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Drugs
Diseases
GWAS
Malaria (
31844061
)
Metabolite levels (Dihydroxy docosatrienoic acid) (
23934736
)
Autism spectrum disorder or schizophrenia (
28540026
)
Interacting Genes
19 interacting genes:
APC
CREBBP
CSNK2A1
EP300
HDAC1
IPO5
KPNB1
NFX1
NUP133
NUP155
NUP62
NUP88
NXF1
RAE1
RCC1
SEC13
TNPO1
TNPO2
TPR
13 interacting genes:
ADGRF5
CFAP43
CLDN12
EGFR
HAPLN2
HSPB1
LTB4R2
NUP98
RAB11A
SEC16B
SEC31A
TRAF5
WDR44
Entrez ID
4928
6396
HPRD ID
03012
02538
Ensembl ID
ENSG00000110713
ENSG00000157020
Uniprot IDs
P52948
A8MWR8
P55735
PDB IDs
1KO6
2Q5X
2Q5Y
3MMY
4OWR
5A9Q
6BZM
3BG0
3BG1
5A9Q
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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