KLRC1 and VTI1B

Data Source:
BioGRID (two hybrid)

		KLRC1	VTI1B
Description		killer cell lectin like receptor C1	vesicle transport through interaction with t-SNAREs 1B
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Receptor Complex	Extracellular Region Lysosomal Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Synaptic Vesicle ER To Golgi Transport Vesicle Membrane Integral Component Of Membrane Platelet Alpha Granule Lumen SNARE Complex Early Endosome Membrane Late Endosome Membrane Vesicle Neuronal Cell Body Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Recycling Endosome Recycling Endosome Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding MHC Class I Protein Complex Binding Carbohydrate Binding HLA-E Specific Inhibitory MHC Class Ib Receptor Activity Protein Antigen Binding	SNARE Binding SNAP Receptor Activity Protein Binding Chloride Channel Inhibitor Activity
	Biological Process	Negative Regulation Of T Cell Mediated Cytotoxicity CD8-positive, Gamma-delta Intraepithelial T Cell Differentiation Natural Killer Cell Inhibitory Signaling Pathway Cell Surface Receptor Signaling Pathway Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Immune Response	Platelet Degranulation Protein Targeting To Vacuole Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Intra-Golgi Vesicle-mediated Transport Golgi To Vacuole Transport Vesicle Docking Involved In Exocytosis Vesicle-mediated Transport Retrograde Transport, Endosome To Golgi Vesicle Fusion With Golgi Apparatus Membrane Fusion Autophagosome Maturation Regulation Of Protein Localization To Plasma Membrane
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Platelet degranulation
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Granulocyte percentage of myeloid white cells ( 27863252) High light scatter reticulocyte count ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 27863252) Monocyte percentage of white cells ( 27863252) Reticulocyte count ( 32888494)	Blood protein levels ( 30072576)
Interacting Genes		45 interacting genes: ATP6V0B ATP6V0C BMP10 BRICD5 C3orf52 CD151 CD82 CGRRF1 CLDN11 CLEC2D CLEC7A CLRN2 CTXN3 CXCL14 CYB561A3 EMP1 EMP3 ERMP1 GJB2 GJB4 GJB6 GPR61 HLA-E KLRD1 KLRG1 LSMEM2 MAL MALL MS4A13 NKG7 PLP1 PMP22 PTPN11 PTPN6 SFTPC TMEM182 TMEM262 TMEM54 TMPPE TSPO2 UNC93B1 UPK1B VAMP5 VTI1B ZFPL1	35 interacting genes: AQP6 ASGR2 CD46 CD79A CLINT1 CRB3 CREB3 ERGIC3 FCGR1A GOLGB1 GPR35 GPX8 JAGN1 KASH5 KLRC1 KRTAP10-7 LDLRAD1 LMNA MANBAL PTPN5 REEP4 RNASEK SLC16A7 SLC35C2 STX1A STX2 STX4 STX7 STX8 SYNE4 TMEM14B TMEM234 TMEM51 TNK2 TRIM59
Entrez ID		3821	10490
HPRD ID		01192	04440
Ensembl ID		ENSG00000134545	ENSG00000100568
Uniprot IDs		P26715	Q9UEU0
PDB IDs		2RMX 2YU7 3BDW 3CDG 3CII	2V8S
Enriched GO Terms of Interacting Partners?
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