KIF3C and MCC

Data Source:
BioGRID (two hybrid)

		KIF3C	MCC
Description		kinesin family member 3C	MCC regulator of WNT signaling pathway
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GO Annotations	Cellular Component	Cytosol Kinesin Complex Microtubule Cilium Ciliary Tip	Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Lamellipodium Cytoplasmic Ribonucleoprotein Granule
	Molecular Function	Motor Activity Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATPase Activity	Protein Binding Signaling Receptor Activity
	Biological Process	Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Microtubule-based Movement Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Intraciliary Transport Involved In Cilium Assembly Organelle Transport Along Microtubule	Signal Transduction Negative Regulation Of Epithelial Cell Migration Wnt Signaling Pathway Establishment Of Protein Localization Negative Regulation Of Epithelial Cell Proliferation Negative Regulation Of Canonical Wnt Signaling Pathway
Pathways		MHC class II antigen presentation Intraflagellar transport COPI-dependent Golgi-to-ER retrograde traffic Kinesins Kinesins
Drugs
Diseases
GWAS		Atrial fibrillation ( 30061737 29892015)	Adult body size ( 32376654) Brain cytoarchitecture ( 20308991) Cerebral amyloid angiopathy ( 25188341) Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189) Height ( 31562340) Metabolite levels ( 23823483) Neurofibrillary tangles ( 31497858) Nicotine dependence symptom count ( 25555482) Triglyceride levels ( 32203549)
Interacting Genes		5 interacting genes: CDC5L DISC1 KIF3A MCC TFIP11	79 interacting genes: ALDOB ANP32B APP BAAT C8orf33 C8orf48 CBX5 CBX8 CCDC112 CCDC146 CCDC180 CCDC185 CCDC187 CDC14B CDK8 CDKL3 CEP57L1 CEP95 CFAP58 CSNK1E CYLC2 DNAAF4 DYNC1I1 ELOA ERBIN ESRRG FAM161A FGF16 FRAT2 GTF2E2 HEMGN HSD17B3 IMP3 KAT5 KIF3C KIFC3 LRRC45 MAGEE1 MSANTD3 MTNR1A NANS NEK2 NFKBIB NOL12 PCCA PNKP POLL PRPF18 RASAL2 RCOR3 SEC61B SFRP4 SLTM SLU7 SYT17 SYT6 TCEA2 TCEANC TGFB1 THAP7 TRMO TRMT2A TSHZ2 TSTD2 TXLNA UTP14C ZBTB48 ZNF12 ZNF189 ZNF202 ZNF264 ZNF3 ZNF35 ZNF417 ZNF438 ZNF497 ZNF543 ZNF648 ZNF792
Entrez ID		3797	4163
HPRD ID		04164	01157
Ensembl ID		ENSG00000084731	ENSG00000171444
Uniprot IDs		A2RU78 O14782	P23508
PDB IDs		3B6V	6MTU 6MTV
Enriched GO Terms of Interacting Partners?
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