KCNJ5 and KCNJ15

Data Source:
BioGRID (two hybrid)

		KCNJ5	KCNJ15
Description		potassium inwardly rectifying channel subfamily J member 5	potassium inwardly rectifying channel subfamily J member 15
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Voltage-gated Potassium Channel Complex External Side Of Plasma Membrane T-tubule	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Inward Rectifier Potassium Channel Activity Protein Binding G-protein Activated Inward Rectifier Potassium Channel Activity Voltage-gated Potassium Channel Activity Involved In Atrial Cardiac Muscle Cell Action Potential Repolarization Voltage-gated Potassium Channel Activity Involved In Ventricular Cardiac Muscle Cell Action Potential Repolarization	Inward Rectifier Potassium Channel Activity Protein Binding
	Biological Process	Potassium Ion Transport Regulation Of Ion Transmembrane Transport Regulation Of Heart Rate By Cardiac Conduction Membrane Repolarization During Atrial Cardiac Muscle Cell Action Potential Membrane Repolarization During Ventricular Cardiac Muscle Cell Action Potential Ventricular Cardiac Muscle Cell Membrane Repolarization Potassium Ion Import Across Plasma Membrane	Potassium Ion Transport Regulation Of Ion Transmembrane Transport Potassium Ion Import Across Plasma Membrane
Pathways		Activation of G protein gated Potassium channels Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits	Activation of G protein gated Potassium channels Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs		Ethanol Ifenprodil	Yohimbine Butamben
Diseases		Long QT syndrome, including: Romano-Ward syndrome; Jervell and Lange-Nielsen syndrome (JLNS)
GWAS		Atrial fibrillation ( 28416818 30061737 29892015) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Refractive error ( 32231278) Resting heart rate ( 27798624) Spherical equivalent or myopia (age of diagnosis) ( 29808027)	Basophil count ( 32888494) Basophil percentage of white cells ( 32888494) Height ( 31562340) Metabolite levels ( 23823483) Non-response to antidepressants and depression ( 27622933)
Interacting Genes		3 interacting genes: ADRB2 KCNJ15 KCNJ3	6 interacting genes: IL16 KCNJ16 KCNJ2 KCNJ5 PATJ SNTA1
Entrez ID		3762	3772
HPRD ID		09010	03659
Ensembl ID		ENSG00000120457	ENSG00000157551
Uniprot IDs		A0A5J6E2W8 P48544	Q99712
PDB IDs
Enriched GO Terms of Interacting Partners?
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