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KCNJ5
Description
potassium inwardly rectifying channel subfamily J member 5
Image
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Voltage-gated Potassium Channel Complex
External Side Of Plasma Membrane
T-tubule
Molecular Function
Inward Rectifier Potassium Channel Activity
Protein Binding
G-protein Activated Inward Rectifier Potassium Channel Activity
Voltage-gated Potassium Channel Activity Involved In Atrial Cardiac Muscle Cell Action Potential Repolarization
Voltage-gated Potassium Channel Activity Involved In Ventricular Cardiac Muscle Cell Action Potential Repolarization
Biological Process
Potassium Ion Transport
Regulation Of Ion Transmembrane Transport
Regulation Of Heart Rate By Cardiac Conduction
Membrane Repolarization During Atrial Cardiac Muscle Cell Action Potential
Membrane Repolarization During Ventricular Cardiac Muscle Cell Action Potential
Ventricular Cardiac Muscle Cell Membrane Repolarization
Potassium Ion Import Across Plasma Membrane
Pathways
Activation of G protein gated Potassium channels
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs
Ethanol
Ifenprodil
Diseases
Long QT syndrome, including: Romano-Ward syndrome; Jervell and Lange-Nielsen syndrome (JLNS)
GWAS
Atrial fibrillation (
28416818
30061737
29892015
)
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Refractive error (
32231278
)
Resting heart rate (
27798624
)
Spherical equivalent or myopia (age of diagnosis) (
29808027
)
Interacting Genes
3 interacting genes:
ADRB2
KCNJ15
KCNJ3
Entrez ID
3762
HPRD ID
09010
Ensembl ID
ENSG00000120457
Uniprot IDs
A0A5J6E2W8
P48544
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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