NDUFS7 and DPCD

Data Source:
BioGRID (affinity chromatography technology)

		NDUFS7	DPCD
Description		NADH:ubiquinone oxidoreductase core subunit S7	deleted in primary ciliary dyskinesia homolog (mouse)
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrial Respiratory Chain Complex I Mitochondrial Matrix	Extracellular Region Nucleus
	Molecular Function	NADH Dehydrogenase Activity Protein Binding NADH Dehydrogenase (ubiquinone) Activity Oxidoreductase Activity, Acting On NAD(P)H, Quinone Or Similar Compound As Acceptor Metal Ion Binding Quinone Binding 4 Iron, 4 Sulfur Cluster Binding	Protein Binding
	Biological Process	Mitochondrial Electron Transport, NADH To Ubiquinone Aerobic Respiration Electron Transport Coupled Proton Transport Mitochondrial Respiratory Chain Complex I Assembly	Epithelial Cilium Movement Involved In Extracellular Fluid Movement Spermatogenesis Determination Of Left/right Symmetry Lateral Ventricle Development Third Ventricle Development Flagellated Sperm Motility Left/right Pattern Formation
Pathways		Respiratory electron transport Complex I biogenesis
Drugs		NADH
Diseases		Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS			Mean corpuscular volume ( 32888494)
Interacting Genes		3 interacting genes: ARRB2 ENO2 MT-ND1	2 interacting genes: APP RUVBL2
Entrez ID		374291	25911
HPRD ID		03491	13247
Ensembl ID		ENSG00000115286	ENSG00000166171
Uniprot IDs		O75251 Q6ZS38 Q7LD69	Q5JQQ4 Q9BVM2
PDB IDs		5XTB 5XTD 5XTH 5XTI
Enriched GO Terms of Interacting Partners?
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