Wiki-MPM

  • About
  • Search
  • Browse
  • People
  • Funding
  • Updates

NDUFS7

Description NADH:ubiquinone oxidoreductase core subunit S7
Image
GO Annotations Cellular Component
  • Mitochondrial Respiratory Chain Complex I
  • Mitochondrial Matrix
Molecular Function
  • NADH Dehydrogenase Activity
  • Protein Binding
  • NADH Dehydrogenase (ubiquinone) Activity
  • Oxidoreductase Activity, Acting On NAD(P)H, Quinone Or Similar Compound As Acceptor
  • Metal Ion Binding
  • Quinone Binding
  • 4 Iron, 4 Sulfur Cluster Binding
Biological Process
  • Mitochondrial Electron Transport, NADH To Ubiquinone
  • Aerobic Respiration
  • Electron Transport Coupled Proton Transport
  • Mitochondrial Respiratory Chain Complex I Assembly
Pathways
  • Respiratory electron transport
  • Complex I biogenesis
Drugs
  • NADH
Diseases
  • Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS
Novel Interacting Genes 1 novel interacting genes: DPCD
Interacting Genes 3 interacting genes: ARRB2 ENO2 MT-ND1
Entrez ID 374291
HPRD ID 03491
Ensembl ID ENSG00000115286
Uniprot IDs O75251 Q6ZS38 Q7LD69
PDB IDs 5XTB 5XTD 5XTH 5XTI
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025