NDUFS7 and ENO2

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NDUFS7	ENO2
Description		NADH:ubiquinone oxidoreductase core subunit S7	enolase 2
Image
GO Annotations	Cellular Component	Mitochondrial Respiratory Chain Complex I Mitochondrial Matrix	Phosphopyruvate Hydratase Complex Photoreceptor Inner Segment Extracellular Space Cytosol Plasma Membrane Membrane Perikaryon Extracellular Exosome
	Molecular Function	NADH Dehydrogenase Activity Protein Binding NADH Dehydrogenase (ubiquinone) Activity Oxidoreductase Activity, Acting On NAD(P)H, Quinone Or Similar Compound As Acceptor Metal Ion Binding Quinone Binding 4 Iron, 4 Sulfur Cluster Binding	Magnesium Ion Binding Phosphopyruvate Hydratase Activity Protein Binding
	Biological Process	Mitochondrial Electron Transport, NADH To Ubiquinone Aerobic Respiration Electron Transport Coupled Proton Transport Mitochondrial Respiratory Chain Complex I Assembly	Gluconeogenesis Glycolytic Process Regulation Of Vacuole Fusion, Non-autophagic Canonical Glycolysis
Pathways		Respiratory electron transport Complex I biogenesis	Glycolysis Gluconeogenesis
Drugs		NADH	2-Phosphoglycolic Acid
Diseases		Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS
Interacting Genes		3 interacting genes: ARRB2 ENO2 MT-ND1	25 interacting genes: A2M ACD AKT1 ANXA11 BMERB1 C6orf47 ENSA EXOC5 HABP4 HK1 HSF1 IL17B MAP4 MTNR1A NAT9 NDUFS7 POT1 SIGIRR SNUPN ST3GAL2 SUMO4 TERF1 TINF2 TUBA4A UBE2C
Entrez ID		374291	2026
HPRD ID		03491	00573
Ensembl ID		ENSG00000115286	ENSG00000111674
Uniprot IDs		O75251 Q6ZS38 Q7LD69	P09104 Q6FHV6
PDB IDs		5XTB 5XTD 5XTH 5XTI	1TE6 2AKM 2AKZ 3UCC 3UCD 3UJE 3UJF 3UJR 3UJS 4ZA0 4ZCW 5EU9 5IDZ 5TD9 5TIJ
Enriched GO Terms of Interacting Partners?
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