JUND and SLC25A12

Data Source:
BioGRID (pull down)

		JUND	SLC25A12
Description		JunD proto-oncogene, AP-1 transcription factor subunit	solute carrier family 25 member 12
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GO Annotations	Cellular Component	Chromatin Nucleoplasm Transcription Regulator Complex Protein-DNA Complex Transcription Factor AP-1 Complex	Mitochondrion Mitochondrial Inner Membrane Integral Component Of Membrane
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Transcription Factor Binding Nuclear Receptor Binding Enzyme Binding Sequence-specific Double-stranded DNA Binding	L-glutamate Transmembrane Transporter Activity Calcium Ion Binding L-aspartate Transmembrane Transporter Activity Transmembrane Transporter Activity Identical Protein Binding
	Biological Process	Osteoblast Development Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Aging Circadian Rhythm Response To Light Stimulus Response To Mechanical Stimulus Response To Organic Cyclic Compound Response To Lipopolysaccharide Regulation Of Cell Population Proliferation Response To Peptide Hormone Positive Regulation Of Osteoblast Differentiation Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Cycle Cellular Response To Calcium Ion	Gluconeogenesis Glutamate Biosynthetic Process Transport Positive Regulation Of Glucose Metabolic Process Aspartate Transmembrane Transport L-glutamate Transmembrane Transport Positive Regulation Of Myelination Malate-aspartate Shuttle Response To Calcium Ion L-aspartate Transmembrane Transport Negative Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate Positive Regulation Of ATP Biosynthetic Process
Pathways		Estrogen-dependent gene expression NGF-stimulated transcription NGF-stimulated transcription	Mitochondrial protein import Gluconeogenesis Aspartate and asparagine metabolism
Drugs			Aspartic acid
Diseases
GWAS		Autoimmune thyroid disease ( 32581359) Bronchodilator response in asthma ( 25562107) Estimated glomerular filtration rate ( 31015462 30604766) Hand grip strength ( 29691431) Systemic lupus erythematosus ( 33536424) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for body mass index ( 25673412) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist-to-hip ratio adjusted for BMI in non-smokers ( 28443625) Waist-to-hip ratio adjusted for body mass index ( 25673412) White blood cell count (monocyte) ( 28158719)	Amyotrophic lateral sclerosis (sporadic) ( 24529757) Refractive error ( 32231278)
Interacting Genes		30 interacting genes: ACTR3 ATF3 BATF BCL6 BRCA1 CCND1 COP1 COPS5 DDIT3 EP300 ESR1 FOS FOSB FOSL2 HINFP JDP2 LINC00461 MAPK1 MAPK3 MAPK8 MAPK9 MDM2 MEN1 NFE2L1 NFE2L2 PPARG SLC25A12 SMAD3 SMAD4 TBP	1 interacting genes: JUND
Entrez ID		3727	8604
HPRD ID		01304	04719
Ensembl ID		ENSG00000130522	ENSG00000115840
Uniprot IDs		P17535	O75746
PDB IDs		3U86 5VPA 5VPB 5VPC 5VPD 5VPE 5VPF	4P5X 4P60
Enriched GO Terms of Interacting Partners?
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