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SLC25A12

Description solute carrier family 25 member 12
Image
GO Annotations Cellular Component
  • Mitochondrion
  • Mitochondrial Inner Membrane
  • Integral Component Of Membrane
Molecular Function
  • L-glutamate Transmembrane Transporter Activity
  • Calcium Ion Binding
  • L-aspartate Transmembrane Transporter Activity
  • Transmembrane Transporter Activity
  • Identical Protein Binding
Biological Process
  • Gluconeogenesis
  • Glutamate Biosynthetic Process
  • Transport
  • Positive Regulation Of Glucose Metabolic Process
  • Aspartate Transmembrane Transport
  • L-glutamate Transmembrane Transport
  • Positive Regulation Of Myelination
  • Malate-aspartate Shuttle
  • Response To Calcium Ion
  • L-aspartate Transmembrane Transport
  • Negative Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate
  • Positive Regulation Of ATP Biosynthetic Process
Pathways
  • Mitochondrial protein import
  • Gluconeogenesis
  • Aspartate and asparagine metabolism
Drugs
  • Aspartic acid
Diseases
GWAS
  • Amyotrophic lateral sclerosis (sporadic) ( 24529757)
  • Refractive error ( 32231278)
Novel Interacting Genes 1 novel interacting genes: GPD2
Interacting Genes 1 interacting genes: JUND
Entrez ID 8604
HPRD ID 04719
Ensembl ID ENSG00000115840
Uniprot IDs O75746
PDB IDs 4P5X 4P60
Enriched GO Terms of Interacting Partners?
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