ITGAE and CHFR

Data Source:
HPRD (two hybrid)

		ITGAE	CHFR
Description		integrin subunit alpha E	checkpoint with forkhead and ring finger domains
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integrin Complex External Side Of Plasma Membrane	Nucleus PML Body
	Molecular Function	Metal Ion Binding	Nucleotide Binding Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Cell Adhesion Integrin-mediated Signaling Pathway Extracellular Matrix Organization	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Mitotic Cell Cycle Checkpoint Protein Ubiquitination Modification-dependent Protein Catabolic Process Positive Regulation Of Protein Ubiquitination Protein Destabilization Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Meiotic Spindle Checkpoint Cell Division
Pathways		Integrin cell surface interactions
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder ( 18839057)	Cognitive function ( 24684796) Height ( 31562340) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Refractive error ( 32231278) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258) Systolic blood pressure x quantitative lifestyle risk score interaction (1df test) ( 32227373) Systolic blood pressure x quantitative lifestyle risk score interaction (2df test) ( 32227373)
Interacting Genes		5 interacting genes: CDH1 CHFR EED ITGB7 TRIM54	30 interacting genes: AURKA BRD4 CBLC EEF1G GABBR1 GRB10 GRB14 HDAC1 HDAC2 ITGAE PML RNF125 RNF7 SIRT1 SMARCA4 SMARCB1 SMARCD1 TRIM9 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2I UBE2L1 UBE2N UBE2W WDR47
Entrez ID		3682	55743
HPRD ID		05249	05552
Ensembl ID		ENSG00000083457	ENSG00000072609
Uniprot IDs		P38570	Q96EP1
PDB IDs			1LGP 1LGQ 2XOC 2XOY 2XOZ 2XP0
Enriched GO Terms of Interacting Partners?
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