ITGAE and ITGB7

Data Source:
HPRD (in vivo)

		ITGAE	ITGB7
Description		integrin subunit alpha E	integrin subunit beta 7
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integrin Complex External Side Of Plasma Membrane	Plasma Membrane Focal Adhesion Integrin Complex Cell Surface Membrane Integrin Alpha4-beta7 Complex Receptor Complex Extracellular Exosome
	Molecular Function	Metal Ion Binding	Virus Receptor Activity Integrin Binding Protein Binding Signaling Receptor Activity Metal Ion Binding Cell Adhesion Molecule Binding
	Biological Process	Cell Adhesion Integrin-mediated Signaling Pathway Extracellular Matrix Organization	Cell-matrix Adhesion Involved In Ameboidal Cell Migration Cell Adhesion Cell-matrix Adhesion Integrin-mediated Signaling Pathway Cell Migration Extracellular Matrix Organization Cell Adhesion Mediated By Integrin Heterotypic Cell-cell Adhesion Substrate Adhesion-dependent Cell Spreading Receptor Clustering Viral Entry Into Host Cell Regulation Of Immune Response Leukocyte Tethering Or Rolling T Cell Migration
Pathways		Integrin cell surface interactions	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Integrin cell surface interactions
Drugs			R1295 Vedolizumab
Diseases
GWAS		Attention deficit hyperactivity disorder ( 18839057)	Obesity-related traits ( 23251661)
Interacting Genes		5 interacting genes: CDH1 CHFR EED ITGB7 TRIM54	15 interacting genes: CDH1 DAB1 DOK1 EED FLNA FN1 ITGA4 ITGAE MADCAM1 PRKCB PRKCD RACK1 TLN1 TNS2 VCAM1
Entrez ID		3682	3695
HPRD ID		05249	00948
Ensembl ID		ENSG00000083457	ENSG00000139626
Uniprot IDs		P38570	P26010
PDB IDs			2BRQ 3V4P 3V4V
Enriched GO Terms of Interacting Partners?
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