AR and DCC

  • Data Source:
  • BioGRID (two hybrid)

AR

DCC

Description androgen receptor DCC netrin 1 receptor
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Age at first sexual intercourse ( 27089180)
  • Alcoholism (alcohol use disorder factor score) ( 21529783)
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Benign prostatic hyperplasia ( 30988330)
  • Body mass index ( 28892062)
  • Body mass index (ever vs never smoking interaction) ( 23192594)
  • Bortezomib-induced peripheral neuropathy in multiple myeloma ( 28317148)
  • Brain morphology (MOSTest) ( 32665545)
  • Chronic back pain ( 30261039)
  • Coenzyme Q10 levels ( 27149984)
  • Cognitive ability ( 29186694)
  • Cognitive ability (MTAG) ( 29186694)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Depression ( 27089181 29700475)
  • Experiencing mood swings ( 29500382)
  • Feeling fed-up ( 29500382)
  • Feeling miserable ( 29500382)
  • Gallbladder cancer ( 22318345)
  • General cognitive ability ( 29844566)
  • General factor of neuroticism ( 30867560)
  • Glucose homeostasis traits ( 25524916)
  • Gut microbiota relative abundance (unclassified genus belonging to family Clostridiaceae) ( 33208821)
  • Household income (MTAG) ( 31844048)
  • Intelligence (MTAG) ( 29326435)
  • Intraocular pressure ( 30591961)
  • Lung function (FVC) ( 30061609 30804560)
  • Mood instability ( 31168069 29187730)
  • Mosquito bite size ( 28199695)
  • Multisite chronic pain ( 31194737)
  • Neurociticism ( 29500382)
  • Nickel levels ( 26025379)
  • Number of sexual partners ( 30643258)
  • Obesity-related traits ( 23251661)
  • Putamen volume ( 29147026)
  • Response to exercise (triglyceride level interaction) ( 26491034)
  • Response to fenofibrate (total cholesterol levels) ( 27002377)
  • Response to mTOR inhibitor (everolimus) ( 24009623)
  • Risk-taking tendency (4-domain principal component model) ( 30643258)
  • Schizophrenia ( 30285260)
  • Short-term memory (digit-span task) ( 30741946)
  • Smoking behaviour (cigarettes smoked per day) ( 27393504)
  • Smoking status (ever vs never smokers) ( 30643258)
  • Subcortical brain region volumes ( 25607358)
  • Survival in colorectal cancer (distant metastatic) ( 26586795)
Interacting Genes 265 interacting genes: ABL1 ABL2 ACTB AHR AKT1 APOL2 APPBP2 ARID5A ATF2 BAG1 BLK BLNK BRCA1 BTK CACUL1 CALM1 CALR CASP1 CASP3 CASP7 CASP8 CAV1 CCAR2 CCND1 CCNE1 CCNH CDC25A CDC25B CDC37 CDK1 CDK6 CDK7 CDK9 CEBPA CEBPB CHD8 COX5B CREBBP CRK CTDSP2 CTNNB1 CUL4B DAP3 DAXX DCAF6 DCC DDB2 DDC DENND5A EED EFCAB6 EGFR ELF3 EP300 ERCC2 ERCC3 ESR1 ETV5 EZH2 FES FGR FHL2 FLNA FOXA1 FOXG1 FOXO1 GADD45GIP1 GAK GAPDH GLI2 GRAP2 GRB2 GRB7 GRIP1 GSK3B GSN GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 HCK HDAC1 HDAC3 HDAC4 HIF1A HIPK3 HMGB1 HMGB2 HOTAIR HSH2D HSP90AA1 IARS1 IDE IFI16 IL6ST INPPL1 JMJD1C JUN KAT2B KAT5 KAT7 KDM1A KIF1A KIFAP3 KLK2 LCK LCOR LYN MAGEA11 MAPK1 MATK MDM2 MDN1 MED1 MED12L MED14 MED24 MLH3 MYBBP1A MYLIP NCOA1 NCOA2 NCOA3 NCOA4 NCOA6 NCOR1 NCOR2 NDE1 NELFCD NFKB1 NISCH NLRP10 NONO NR0B1 NR0B2 NR2C1 NR2C2 NR3C1 NR3C2 NR5A1 NRIP1 NSD1 NSD2 PA2G4 PAK6 PELP1 PIAS1 PIAS2 PIAS3 PIAS4 PIK3R1 PIK3R2 PIK3R3 PLCG1 PLCG2 PNRC1 PNRC2 POU2F1 POU2F2 POU5F1 PRKG1 PRMT1 PRPF6 PSMC3IP PTEN PTK6 PTPN11 PXN RAC3 RACK1 RAD54L2 RAD9A RAF1 RAN RANBP9 RASA1 RB1 RBAK RCHY1 REL RELA REPS2 RNASEL RNF14 RNF4 RNF6 RUNX1 RUNX2 SART3 SFPQ SH2D1A SH2D1B SH2D2A SH2D3C SH3YL1 SHB SHC1 SHC3 SHC4 SHE SIRT1 SLC25A4 SMAD1 SMAD3 SMAD4 SMARCA2 SMARCA4 SMARCD1 SMARCE1 SOCS3 SOCS6 SP1 SPDEF SPOP SRC SREBF1 SRY STAP1 STAT3 STUB1 SUMO1 SUV39H2 SVIL SYK TADA3 TAF1 TBP TCF20 TCF4 TCF7L2 TDG TGFB1I1 TGIF1 TLE5 TMF1 TNK2 TNS1 TNS4 TPD52 TRIM24 TRIP4 TSG101 TXNDC5 UBE2I UBE3A USP10 UXT VAV1 VAV2 VAV3 VCP VHL WIPI1 XRCC5 XRCC6 YES1 YWHAQ ZBTB1 ZBTB16 ZBTB32 ZBTB7A ZMIZ1 ZMIZ2 ZNF451 28 interacting genes: ADORA2B ALDOB ANP32B APPL1 AR BARD1 CASP3 CASP9 CORO2A CTSV FBP1 HEMGN MAPK3 MAZ NCK1 NTN1 PITPNA PTK2 RASA1 RPL5 SFRP2 SIAH1 SIAH2 TBC1D2 TDRD7 TMOD1 TRMO TSTD2
Entrez ID 367 1630
HPRD ID 02437 00391
Ensembl ID ENSG00000169083 ENSG00000187323
Uniprot IDs A0A087WUX9 F1D8N5 G4VV16 P10275 Q9NUA2 P43146 Q49AK4
PDB IDs 1E3G 1GS4 1T5Z 1T63 1T65 1XJ7 1XOW 1XQ3 1Z95 2AM9 2AMA 2AMB 2AO6 2AX6 2AX7 2AX8 2AX9 2AXA 2HVC 2OZ7 2PIO 2PIP 2PIQ 2PIR 2PIT 2PIU 2PIV 2PIW 2PIX 2PKL 2PNU 2Q7I 2Q7J 2Q7K 2Q7L 2YHD 2YLO 2YLP 2YLQ 2Z4J 3B5R 3B65 3B66 3B67 3B68 3BTR 3L3X 3L3Z 3RLJ 3RLL 3V49 3V4A 3ZQT 4HLW 4K7A 4OEA 4OED 4OEY 4OEZ 4OFR 4OFU 4OGH 4OH5 4OH6 4OHA 4OIL 4OIU 4OJ9 4OJB 4OK1 4OKB 4OKT 4OKW 4OKX 4OLM 4QL8 5CJ6 5JJM 5T8E 5T8J 5V8Q 5VO4 2ED7 2ED8 2ED9 2EDB 2EDD 2EDE 3AU4 4URT 5X83
Enriched GO Terms of Interacting Partners?
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