Description |
androgen receptor |
DCC netrin 1 receptor |
Image |
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Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
- Diethylstilbestrol
- Levonorgestrel
- Progesterone
- Spironolactone
- Flutamide
- Oxandrolone
- Fluphenazine
- Testosterone
- Mitotane
- Estrone
- Nilutamide
- Tamoxifen
- Norethisterone
- Drostanolone
- Norgestimate
- Nandrolone phenpropionate
- Ketoconazole
- Acetophenazine
- Bicalutamide
- Fluoxymesterone
- Drospirenone
- Danazol
- Testosterone propionate
- Oxybenzone
- 1-Testosterone
- Boldenone
- Calusterone
- Periciazine
- Prasterone
- Flufenamic acid
- Stanolone
- (R)-Bicalutamide
- Metribolone
- (3AALPHA,4ALPHA,7ALPHA,7AALPHA)- 3A,4,7,7A-TETRAHYDRO-2-(4-NITRO-1-NAPHTHALENYL)-4,7-ETHANO-1H-ISOINDOLE-1,3(2H)-DIONE
- Cyproterone acetate
- LGD2941
- Dimethylcurcumin
- Oxymetholone
- Methyltestosterone
- Norelgestromin
- Stanozolol
- Tetrahydrogestrinone
- (2S)-N-(4-cyano-3-iodophenyl)-3-(4-cyanophenoxy)-2-hydroxy-2-methylpropanamide
- BMS-564929
- S-23
- phenoxy)propyl]amino}-2-(trifluoromethyl)benzonitrile
- (2S)-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-3-(pentafluorophenoxy)propanamide
- Andarine
- (R)-3-BROMO-2-HYDROXY-2-METHYL-N-[4-NITRO-3-(TRIFLUOROMETHYL)PHENYL]PROPANAMIDE
- (5S,8R,9S,10S,13R,14S,17S)-13-{2-[(3,5-DIFLUOROBENZYL)OXY]ETHYL}-17-HYDROXY-10-METHYLHEXADECAHYDRO-3H-CYCLOPENTA[A]PHENANTHREN-3-ONE
- S-3-(4-FLUOROPHENOXY)-2-HYDROXY-2-METHYL-N-[4-NITRO-3-(TRIFLUOROMETHYL)PHENYL]PROPANAMIDE
- 1-TERT-BUTYL-3-(2,5-DIMETHYLBENZYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE
- 4-[(7R,7AS)-7-HYDROXY-1,3-DIOXOTETRAHYDRO-1H-PYRROLO[1,2-C]IMIDAZOL-2(3H)-YL]-1-NAPHTHONITRILE
- 2-chloro-4-{[(1R,3Z,7S,7aS)-7-hydroxy-1-(trifluoromethyl)tetrahydro-1H-pyrrolo[1,2-c][1,3]oxazol-3-ylidene]amino}-3-methylbenzonitrile
- LGD-2226
- 3-[(4-AMINO-1-TERT-BUTYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL)METHYL]PHENOL
- Triclosan
- Nandrolone decanoate
- Ulipristal
- Enzalutamide
- Eugenol
- Dienogest
- Norethynodrel
- Norgestrel
- Homosalate
- Enzacamene
- Mibolerone
- Phenothiazine
- Gestrinone
- Apalutamide
- Clascoterone
- Darolutamide
- Esculin
- Ligandrol
- Testosterone cypionate
- Testosterone enanthate
- Testosterone undecanoate
- Stanolone acetate
- Segesterone acetate
- Boldenone undecylenate
- Echinacoside
- Ketodarolutamide
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Diseases |
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GWAS |
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- Age at first sexual intercourse ( 27089180)
- Alcoholism (alcohol use disorder factor score) ( 21529783)
- anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
- Benign prostatic hyperplasia ( 30988330)
- Body mass index ( 28892062)
- Body mass index (ever vs never smoking interaction) ( 23192594)
- Bortezomib-induced peripheral neuropathy in multiple myeloma ( 28317148)
- Brain morphology (MOSTest) ( 32665545)
- Chronic back pain ( 30261039)
- Coenzyme Q10 levels ( 27149984)
- Cognitive ability ( 29186694)
- Cognitive ability (MTAG) ( 29186694)
- Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
- Depression ( 27089181 29700475)
- Experiencing mood swings ( 29500382)
- Feeling fed-up ( 29500382)
- Feeling miserable ( 29500382)
- Gallbladder cancer ( 22318345)
- General cognitive ability ( 29844566)
- General factor of neuroticism ( 30867560)
- Glucose homeostasis traits ( 25524916)
- Gut microbiota relative abundance (unclassified genus belonging to family Clostridiaceae) ( 33208821)
- Household income (MTAG) ( 31844048)
- Intelligence (MTAG) ( 29326435)
- Intraocular pressure ( 30591961)
- Lung function (FVC) ( 30061609 30804560)
- Mood instability ( 31168069 29187730)
- Mosquito bite size ( 28199695)
- Multisite chronic pain ( 31194737)
- Neurociticism ( 29500382)
- Nickel levels ( 26025379)
- Number of sexual partners ( 30643258)
- Obesity-related traits ( 23251661)
- Putamen volume ( 29147026)
- Response to exercise (triglyceride level interaction) ( 26491034)
- Response to fenofibrate (total cholesterol levels) ( 27002377)
- Response to mTOR inhibitor (everolimus) ( 24009623)
- Risk-taking tendency (4-domain principal component model) ( 30643258)
- Schizophrenia ( 30285260)
- Short-term memory (digit-span task) ( 30741946)
- Smoking behaviour (cigarettes smoked per day) ( 27393504)
- Smoking status (ever vs never smokers) ( 30643258)
- Subcortical brain region volumes ( 25607358)
- Survival in colorectal cancer (distant metastatic) ( 26586795)
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Interacting Genes |
265 interacting genes:
ABL1
ABL2
ACTB
AHR
AKT1
APOL2
APPBP2
ARID5A
ATF2
BAG1
BLK
BLNK
BRCA1
BTK
CACUL1
CALM1
CALR
CASP1
CASP3
CASP7
CASP8
CAV1
CCAR2
CCND1
CCNE1
CCNH
CDC25A
CDC25B
CDC37
CDK1
CDK6
CDK7
CDK9
CEBPA
CEBPB
CHD8
COX5B
CREBBP
CRK
CTDSP2
CTNNB1
CUL4B
DAP3
DAXX
DCAF6
DCC
DDB2
DDC
DENND5A
EED
EFCAB6
EGFR
ELF3
EP300
ERCC2
ERCC3
ESR1
ETV5
EZH2
FES
FGR
FHL2
FLNA
FOXA1
FOXG1
FOXO1
GADD45GIP1
GAK
GAPDH
GLI2
GRAP2
GRB2
GRB7
GRIP1
GSK3B
GSN
GTF2F1
GTF2F2
GTF2H1
GTF2H2
GTF2H3
HCK
HDAC1
HDAC3
HDAC4
HIF1A
HIPK3
HMGB1
HMGB2
HOTAIR
HSH2D
HSP90AA1
IARS1
IDE
IFI16
IL6ST
INPPL1
JMJD1C
JUN
KAT2B
KAT5
KAT7
KDM1A
KIF1A
KIFAP3
KLK2
LCK
LCOR
LYN
MAGEA11
MAPK1
MATK
MDM2
MDN1
MED1
MED12L
MED14
MED24
MLH3
MYBBP1A
MYLIP
NCOA1
NCOA2
NCOA3
NCOA4
NCOA6
NCOR1
NCOR2
NDE1
NELFCD
NFKB1
NISCH
NLRP10
NONO
NR0B1
NR0B2
NR2C1
NR2C2
NR3C1
NR3C2
NR5A1
NRIP1
NSD1
NSD2
PA2G4
PAK6
PELP1
PIAS1
PIAS2
PIAS3
PIAS4
PIK3R1
PIK3R2
PIK3R3
PLCG1
PLCG2
PNRC1
PNRC2
POU2F1
POU2F2
POU5F1
PRKG1
PRMT1
PRPF6
PSMC3IP
PTEN
PTK6
PTPN11
PXN
RAC3
RACK1
RAD54L2
RAD9A
RAF1
RAN
RANBP9
RASA1
RB1
RBAK
RCHY1
REL
RELA
REPS2
RNASEL
RNF14
RNF4
RNF6
RUNX1
RUNX2
SART3
SFPQ
SH2D1A
SH2D1B
SH2D2A
SH2D3C
SH3YL1
SHB
SHC1
SHC3
SHC4
SHE
SIRT1
SLC25A4
SMAD1
SMAD3
SMAD4
SMARCA2
SMARCA4
SMARCD1
SMARCE1
SOCS3
SOCS6
SP1
SPDEF
SPOP
SRC
SREBF1
SRY
STAP1
STAT3
STUB1
SUMO1
SUV39H2
SVIL
SYK
TADA3
TAF1
TBP
TCF20
TCF4
TCF7L2
TDG
TGFB1I1
TGIF1
TLE5
TMF1
TNK2
TNS1
TNS4
TPD52
TRIM24
TRIP4
TSG101
TXNDC5
UBE2I
UBE3A
USP10
UXT
VAV1
VAV2
VAV3
VCP
VHL
WIPI1
XRCC5
XRCC6
YES1
YWHAQ
ZBTB1
ZBTB16
ZBTB32
ZBTB7A
ZMIZ1
ZMIZ2
ZNF451
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28 interacting genes:
ADORA2B
ALDOB
ANP32B
APPL1
AR
BARD1
CASP3
CASP9
CORO2A
CTSV
FBP1
HEMGN
MAPK3
MAZ
NCK1
NTN1
PITPNA
PTK2
RASA1
RPL5
SFRP2
SIAH1
SIAH2
TBC1D2
TDRD7
TMOD1
TRMO
TSTD2
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Entrez ID |
367 |
1630 |
HPRD ID |
02437 |
00391 |
Ensembl ID |
ENSG00000169083
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ENSG00000187323
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Uniprot IDs |
A0A087WUX9
F1D8N5
G4VV16
P10275
Q9NUA2
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P43146
Q49AK4
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PDB IDs |
1E3G
1GS4
1T5Z
1T63
1T65
1XJ7
1XOW
1XQ3
1Z95
2AM9
2AMA
2AMB
2AO6
2AX6
2AX7
2AX8
2AX9
2AXA
2HVC
2OZ7
2PIO
2PIP
2PIQ
2PIR
2PIT
2PIU
2PIV
2PIW
2PIX
2PKL
2PNU
2Q7I
2Q7J
2Q7K
2Q7L
2YHD
2YLO
2YLP
2YLQ
2Z4J
3B5R
3B65
3B66
3B67
3B68
3BTR
3L3X
3L3Z
3RLJ
3RLL
3V49
3V4A
3ZQT
4HLW
4K7A
4OEA
4OED
4OEY
4OEZ
4OFR
4OFU
4OGH
4OH5
4OH6
4OHA
4OIL
4OIU
4OJ9
4OJB
4OK1
4OKB
4OKT
4OKW
4OKX
4OLM
4QL8
5CJ6
5JJM
5T8E
5T8J
5V8Q
5VO4
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2ED7
2ED8
2ED9
2EDB
2EDD
2EDE
3AU4
4URT
5X83
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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