INSRR and CTDSP2

Data Source:
BioGRID (two hybrid)

		INSRR	CTDSP2
Description		insulin receptor related receptor	CTD small phosphatase 2
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Plasma Membrane Insulin Receptor Complex Axon Receptor Complex	Nucleoplasm
	Molecular Function	Transmembrane Receptor Protein Tyrosine Kinase Activity Insulin-activated Receptor Activity Protein Binding ATP Binding Phosphatidylinositol 3-kinase Binding Insulin Receptor Substrate Binding	Phosphoprotein Phosphatase Activity Protein Binding RNA Polymerase II CTD Heptapeptide Repeat Phosphatase Activity Metal Ion Binding Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity
	Biological Process	Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Multicellular Organism Development Insulin Receptor Signaling Pathway Peptidyl-tyrosine Phosphorylation Male Sex Determination Actin Cytoskeleton Reorganization Positive Regulation Of Kinase Activity Protein Autophosphorylation Cellular Response To Alkaline PH	Negative Regulation Of Protein Phosphorylation Protein Dephosphorylation IRE1-mediated Unfolded Protein Response Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways			XBP1(S) activates chaperone genes
Drugs		Fostamatinib
Diseases
GWAS		Uric acid clearance ( 28095793)	Height ( 31562340) Hematocrit ( 32888494) Metabolite levels ( 23823483) Refractive error ( 32231278) Trochanter size ( 31053729)
Interacting Genes		6 interacting genes: CTDSP2 ERBB2 INSR KRT27 MEOX2 STYX	13 interacting genes: AKT1 AR CDCA3 CSF1R EPHA1 EPHA3 INSRR LCN2 N4BP3 POLR2A PTK7 SNAI1 TYRO3
Entrez ID		3645	10106
HPRD ID		00976	12281
Ensembl ID		ENSG00000027644	ENSG00000175215
Uniprot IDs		P14616	A0A024RB65 A0A024RBA6 O14595
PDB IDs			2Q5E
Enriched GO Terms of Interacting Partners?
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