CTDSP2 and INSRR

Data Source:
BioGRID (two hybrid)

		CTDSP2	INSRR
Description		CTD small phosphatase 2	insulin receptor related receptor
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm	Integral Component Of Plasma Membrane Insulin Receptor Complex Axon Receptor Complex
	Molecular Function	Phosphoprotein Phosphatase Activity Protein Binding RNA Polymerase II CTD Heptapeptide Repeat Phosphatase Activity Metal Ion Binding Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity	Transmembrane Receptor Protein Tyrosine Kinase Activity Insulin-activated Receptor Activity Protein Binding ATP Binding Phosphatidylinositol 3-kinase Binding Insulin Receptor Substrate Binding
	Biological Process	Negative Regulation Of Protein Phosphorylation Protein Dephosphorylation IRE1-mediated Unfolded Protein Response Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle	Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Multicellular Organism Development Insulin Receptor Signaling Pathway Peptidyl-tyrosine Phosphorylation Male Sex Determination Actin Cytoskeleton Reorganization Positive Regulation Of Kinase Activity Protein Autophosphorylation Cellular Response To Alkaline PH
Pathways		XBP1(S) activates chaperone genes
Drugs			Fostamatinib
Diseases
GWAS		Height ( 31562340) Hematocrit ( 32888494) Metabolite levels ( 23823483) Refractive error ( 32231278) Trochanter size ( 31053729)	Uric acid clearance ( 28095793)
Interacting Genes		13 interacting genes: AKT1 AR CDCA3 CSF1R EPHA1 EPHA3 INSRR LCN2 N4BP3 POLR2A PTK7 SNAI1 TYRO3	6 interacting genes: CTDSP2 ERBB2 INSR KRT27 MEOX2 STYX
Entrez ID		10106	3645
HPRD ID		12281	00976
Ensembl ID		ENSG00000175215	ENSG00000027644
Uniprot IDs		A0A024RB65 A0A024RBA6 O14595	P14616
PDB IDs		2Q5E
Enriched GO Terms of Interacting Partners?
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