AQP7 and CLCN7

Data Source:
BioGRID (two hybrid)

		AQP7	CLCN7
Description		aquaporin 7	chloride voltage-gated channel 7
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GO Annotations	Cellular Component	Cytoplasm Lipid Droplet Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Cell Cortex Cytoplasmic Vesicle Membrane	Nucleoplasm Lysosomal Membrane Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Urea Transmembrane Transporter Activity Water Channel Activity Glycerol Channel Activity	Voltage-gated Chloride Channel Activity Chloride Channel Activity Protein Binding ATP Binding Chloride Transmembrane Transporter Activity Antiporter Activity
	Biological Process	Water Transport Glycerol Transport Urea Transmembrane Transport	Ion Transmembrane Transport Chloride Transmembrane Transport
Pathways		Transport of glycerol from adipocytes to the liver by Aquaporins Passive transport by Aquaporins	Stimuli-sensing channels
Drugs
Diseases			Osteopetrosis, including: Osteopetrosis, severe neonatal or infantile forms; Osteopetrosis, intermediate forms; Osteopetrosis with renal tubular acidosis; Osteopetrosis, late-onset form type 1; Osteopetrosis, late-onset form type 2; Osteopetrosis, osteoclast poor
GWAS		Lung adenocarcinoma ( 28604730) Urinary albumin excretion ( 30220432)	Acute anterior uveitis in ankylosing spondylitis ( 32492107) Refractive error ( 32231278)
Interacting Genes		4 interacting genes: ABHD16A CLCN7 COMT MFSD6	17 interacting genes: AQP7 CD53 CREB3 GDAP1 GET1 KCNN3 LHFPL5 LMNA LYVE1 MTDH OPRM1 OSTM1 PACS1 SLC38A7 SLC66A2 TLCD4 TMEM179B
Entrez ID		364	1186
HPRD ID		04277	04103
Ensembl ID		ENSG00000165269	ENSG00000103249
Uniprot IDs		B7Z4U2 O14520 Q5T5M0 Q5T5M1 Q6P5T0	P51798
PDB IDs		6KXW 6N1G 6QZI 6QZJ	7BXU 7JM7
Enriched GO Terms of Interacting Partners?
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