CLCN7 and AQP7

Data Source:
BioGRID (two hybrid)

		CLCN7	AQP7
Description		chloride voltage-gated channel 7	aquaporin 7
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GO Annotations	Cellular Component	Nucleoplasm Lysosomal Membrane Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle	Cytoplasm Lipid Droplet Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Cell Cortex Cytoplasmic Vesicle Membrane
	Molecular Function	Voltage-gated Chloride Channel Activity Chloride Channel Activity Protein Binding ATP Binding Chloride Transmembrane Transporter Activity Antiporter Activity	Urea Transmembrane Transporter Activity Water Channel Activity Glycerol Channel Activity
	Biological Process	Ion Transmembrane Transport Chloride Transmembrane Transport	Water Transport Glycerol Transport Urea Transmembrane Transport
Pathways		Stimuli-sensing channels	Transport of glycerol from adipocytes to the liver by Aquaporins Passive transport by Aquaporins
Drugs
Diseases		Osteopetrosis, including: Osteopetrosis, severe neonatal or infantile forms; Osteopetrosis, intermediate forms; Osteopetrosis with renal tubular acidosis; Osteopetrosis, late-onset form type 1; Osteopetrosis, late-onset form type 2; Osteopetrosis, osteoclast poor
GWAS		Acute anterior uveitis in ankylosing spondylitis ( 32492107) Refractive error ( 32231278)	Lung adenocarcinoma ( 28604730) Urinary albumin excretion ( 30220432)
Interacting Genes		17 interacting genes: AQP7 CD53 CREB3 GDAP1 GET1 KCNN3 LHFPL5 LMNA LYVE1 MTDH OPRM1 OSTM1 PACS1 SLC38A7 SLC66A2 TLCD4 TMEM179B	4 interacting genes: ABHD16A CLCN7 COMT MFSD6
Entrez ID		1186	364
HPRD ID		04103	04277
Ensembl ID		ENSG00000103249	ENSG00000165269
Uniprot IDs		P51798	B7Z4U2 O14520 Q5T5M0 Q5T5M1 Q6P5T0
PDB IDs		7BXU 7JM7	6KXW 6N1G 6QZI 6QZJ
Enriched GO Terms of Interacting Partners?
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