INHA and INHBB

Data Source:
HPRD (in vitro)

		INHA	INHBB
Description		inhibin subunit alpha	inhibin subunit beta B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Photoreceptor Inner Segment Extracellular Region Extracellular Space Cytoplasm Inhibin-betaglycan-ActRII Complex Neuronal Cell Body Inhibin A Complex Inhibin B Complex	Extracellular Region Extracellular Space Perinuclear Region Of Cytoplasm Cell Periphery
	Molecular Function	Signaling Receptor Binding Cytokine Activity Hormone Activity Protein Binding Growth Factor Activity Inhibin Binding Protein-containing Complex Binding	Cytokine Activity Hormone Activity Protein Binding Growth Factor Activity Protein Homodimerization Activity Host Cell Surface Receptor Binding
	Biological Process	Skeletal System Development Ovarian Follicle Development Cell Cycle Arrest Signal Transduction Cell Surface Receptor Signaling Pathway Cell-cell Signaling Male Gonad Development Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Cell Differentiation Erythrocyte Differentiation Negative Regulation Of Interferon-gamma Production Regulation Of Cell Population Proliferation Negative Regulation Of Phosphorylation Hemoglobin Biosynthetic Process Negative Regulation Of B Cell Differentiation Negative Regulation Of Macrophage Differentiation Negative Regulation Of Cell Cycle Positive Regulation Of Follicle-stimulating Hormone Secretion Negative Regulation Of Follicle-stimulating Hormone Secretion Regulation Of Cell Cycle SMAD Protein Signal Transduction	Ovarian Follicle Development Defense Response Cellular Response To Starvation Response To Wounding Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Cell Differentiation Negative Regulation Of Hepatocyte Growth Factor Production Cellular Response To Insulin Stimulus Activin Receptor Signaling Pathway Cellular Response To Leptin Stimulus Adhesion Of Symbiont To Host Cell Fat Cell Differentiation Negative Regulation Of Insulin Secretion Positive Regulation Of Follicle-stimulating Hormone Secretion Negative Regulation Of Follicle-stimulating Hormone Secretion Oocyte Development Positive Regulation Of Ovulation SMAD Protein Signal Transduction Positive Regulation Of Apoptotic Signaling Pathway
Pathways		Glycoprotein hormones	Signaling by Activin Signaling by Activin Glycoprotein hormones Antagonism of Activin by Follistatin
Drugs
Diseases		Premature ovarian failure
GWAS			Age-related macular degeneration ( 23326517) Breast cancer ( 27117709) Breast cancer (estrogen-receptor negative) ( 27117709) Breast size ( 22747683 27182965) Obesity ( 21552555) Urate levels ( 31985003 23263486)
Interacting Genes		5 interacting genes: FST INHBA INHBB SIAH1 TGFBR3	12 interacting genes: ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B BMPR2 FNTA IGSF1 INHA INHBA INHBC TDGF1
Entrez ID		3623	3625
HPRD ID		00933	00934
Ensembl ID		ENSG00000123999	ENSG00000163083
Uniprot IDs		P05111	P09529
PDB IDs
Enriched GO Terms of Interacting Partners?
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