INHA and FST

Data Source:
HPRD (in vivo)

		INHA	FST
Description		inhibin subunit alpha	follistatin
Image		No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Photoreceptor Inner Segment Extracellular Region Extracellular Space Cytoplasm Inhibin-betaglycan-ActRII Complex Neuronal Cell Body Inhibin A Complex Inhibin B Complex	Extracellular Region Extracellular Space Nucleus Cytoplasm
	Molecular Function	Signaling Receptor Binding Cytokine Activity Hormone Activity Protein Binding Growth Factor Activity Inhibin Binding Protein-containing Complex Binding	Protein Binding Activin Receptor Antagonist Activity Heparan Sulfate Proteoglycan Binding Activin Binding
	Biological Process	Skeletal System Development Ovarian Follicle Development Cell Cycle Arrest Signal Transduction Cell Surface Receptor Signaling Pathway Cell-cell Signaling Male Gonad Development Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Cell Differentiation Erythrocyte Differentiation Negative Regulation Of Interferon-gamma Production Regulation Of Cell Population Proliferation Negative Regulation Of Phosphorylation Hemoglobin Biosynthetic Process Negative Regulation Of B Cell Differentiation Negative Regulation Of Macrophage Differentiation Negative Regulation Of Cell Cycle Positive Regulation Of Follicle-stimulating Hormone Secretion Negative Regulation Of Follicle-stimulating Hormone Secretion Regulation Of Cell Cycle SMAD Protein Signal Transduction	Negative Regulation Of Transcription By RNA Polymerase II Skeletal System Development Hematopoietic Progenitor Cell Differentiation Multicellular Organism Development Gamete Generation Pattern Specification Process Female Gonad Development Cell Differentiation BMP Signaling Pathway Regulation Of BMP Signaling Pathway Hair Follicle Morphogenesis Negative Regulation Of Activin Receptor Signaling Pathway Odontogenesis Of Dentin-containing Tooth Keratinocyte Proliferation Negative Regulation Of Cell Differentiation Positive Regulation Of Hair Follicle Development
Pathways		Glycoprotein hormones	Antagonism of Activin by Follistatin
Drugs			D-Myo-Inositol-Hexasulphate
Diseases		Premature ovarian failure
GWAS			Acne (severe) ( 24927181 30542056) Alzheimer's disease (late onset) ( 30820047) Central corneal thickness ( 32528159) Estimated glomerular filtration rate ( 31152163) HDL cholesterol levels ( 32203549) Height ( 31562340) High-grade serous ovarian cancer ( 31469419) Intraocular pressure ( 29617998 29235454) Midgestational circulating levels of PCBs ( 28235828) Optic disc size ( 31809533) Refractive error ( 32231278)
Interacting Genes		5 interacting genes: FST INHBA INHBB SIAH1 TGFBR3	14 interacting genes: BEX2 BMP5 C8orf33 CATSPER1 CREB5 FN1 HOXA1 INHA INHBA INHBE MEST TK1 TXN ZNF587
Entrez ID		3623	10468
HPRD ID		00933	00641
Ensembl ID		ENSG00000123999	ENSG00000134363
Uniprot IDs		P05111	A0A024QZU6 P19883
PDB IDs			2B0U 2P6A 3HH2 5JHW
Enriched GO Terms of Interacting Partners?
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