FST and INHBE

Data Source:
HPRD (in vitro)

		FST	INHBE
Description		follistatin	inhibin subunit beta E
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Cytoplasm	Extracellular Space Collagen-containing Extracellular Matrix
	Molecular Function	Protein Binding Activin Receptor Antagonist Activity Heparan Sulfate Proteoglycan Binding Activin Binding	Cytokine Activity Hormone Activity Growth Factor Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Skeletal System Development Hematopoietic Progenitor Cell Differentiation Multicellular Organism Development Gamete Generation Pattern Specification Process Female Gonad Development Cell Differentiation BMP Signaling Pathway Regulation Of BMP Signaling Pathway Hair Follicle Morphogenesis Negative Regulation Of Activin Receptor Signaling Pathway Odontogenesis Of Dentin-containing Tooth Keratinocyte Proliferation Negative Regulation Of Cell Differentiation Positive Regulation Of Hair Follicle Development	Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation SMAD Protein Signal Transduction
Pathways		Antagonism of Activin by Follistatin	Glycoprotein hormones
Drugs		D-Myo-Inositol-Hexasulphate
Diseases
GWAS		Acne (severe) ( 24927181 30542056) Alzheimer's disease (late onset) ( 30820047) Central corneal thickness ( 32528159) Estimated glomerular filtration rate ( 31152163) HDL cholesterol levels ( 32203549) Height ( 31562340) High-grade serous ovarian cancer ( 31469419) Intraocular pressure ( 29617998 29235454) Midgestational circulating levels of PCBs ( 28235828) Optic disc size ( 31809533) Refractive error ( 32231278)	HDL cholesterol ( 30275531) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Platelet count ( 32888494 27863252) Plateletcrit ( 32888494) Red cell distribution width ( 32888494) Urate levels ( 23263486)
Interacting Genes		14 interacting genes: BEX2 BMP5 C8orf33 CATSPER1 CREB5 FN1 HOXA1 INHA INHBA INHBE MEST TK1 TXN ZNF587	1 interacting genes: FST
Entrez ID		10468	83729
HPRD ID		00641	11047
Ensembl ID		ENSG00000134363	ENSG00000139269
Uniprot IDs		A0A024QZU6 P19883	P58166
PDB IDs		2B0U 2P6A 3HH2 5JHW
Enriched GO Terms of Interacting Partners?
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