AQP2 and LMAN2L

Data Source:
BioGRID (affinity chromatography technology)

		AQP2	LMAN2L
Description		aquaporin 2	lectin, mannose binding 2 like
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane Basolateral Plasma Membrane Apical Plasma Membrane Transport Vesicle Membrane Perinuclear Region Of Cytoplasm Recycling Endosome Extracellular Exosome Lumenal Side Of Membrane	Golgi Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Integral Component Of Membrane COPII-coated ER To Golgi Transport Vesicle
	Molecular Function	Water Transmembrane Transporter Activity Protein Binding Glycerol Transmembrane Transporter Activity Water Channel Activity	Protein Binding Mannose Binding Metal Ion Binding
	Biological Process	Renal Water Homeostasis Renal Water Transport Water Transport Glycerol Transport Cellular Response To Water Deprivation Protein Homotetramerization Transmembrane Transport Cellular Response To Copper Ion Cellular Response To Mercury Ion Metanephric Collecting Duct Development	Protein Folding Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Endoplasmic Reticulum Organization Golgi Organization Protein Transport
Pathways		Vasopressin regulates renal water homeostasis via Aquaporins Passive transport by Aquaporins	COPII-mediated vesicle transport Cargo concentration in the ER
Drugs
Diseases		Congenital nephrogenic diabetes insipidus (NDI)
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Allergic rhinitis ( 30013184) Obsessive-compulsive disorder ( 22889921)	anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Bipolar disorder ( 22182935 21926972 31043756 28072414 20351715) Blood protein levels ( 30072576 29875488)
Interacting Genes		60 interacting genes: ACTB BCAP31 C4orf3 CCDC167 CDIPT CERT1 CLCA4 CLDN7 CREB3 CREB3L1 CTSA CXCL16 EEF1A1 EFNA5 ELL2 ERG28 ERGIC3 ERMP1 FAM209A GPAA1 GPX8 IER3 IGFBP5 INSIG2 LEUTX LHFPL5 MRM1 MS4A13 MUC1 NDFIP2 OLFM4 OR10AG1 PANX1 PDZK1IP1 PLP2 PNLIPRP1 RTP2 SLC26A6 SLC30A2 SLC38A7 SLC5A2 SNAP47 SNX5 SPCS1 SSR3 STUB1 STX8 SUPT20H TM9SF2 TMEM109 TMEM218 TMEM230 TMEM236 TMEM60 TMEM86A TMEM97 TRARG1 UBE2J1 VAPB YIPF6	2 interacting genes: MAL ZDHHC17
Entrez ID		359	81562
HPRD ID		00141	17286
Ensembl ID		ENSG00000167580	ENSG00000114988
Uniprot IDs		P41181	B4DI83 B4DVH1 B4E308 Q9H0V9
PDB IDs		4NEF 4OJ2 6QF5
Enriched GO Terms of Interacting Partners?
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