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AQP2 and SLC30A2
Data Source:
BioGRID
(two hybrid)
AQP2
SLC30A2
Description
aquaporin 2
solute carrier family 30 member 2
Image
No pdb structure
GO Annotations
Cellular Component
Golgi Apparatus
Plasma Membrane
Integral Component Of Plasma Membrane
Membrane
Integral Component Of Membrane
Basolateral Plasma Membrane
Apical Plasma Membrane
Transport Vesicle Membrane
Perinuclear Region Of Cytoplasm
Recycling Endosome
Extracellular Exosome
Lumenal Side Of Membrane
Cytoplasm
Lysosomal Membrane
Late Endosome
Plasma Membrane
Integral Component Of Membrane
Intracellular Membrane-bounded Organelle
Molecular Function
Water Transmembrane Transporter Activity
Protein Binding
Glycerol Transmembrane Transporter Activity
Water Channel Activity
Zinc Ion Transmembrane Transporter Activity
Protein Binding
Identical Protein Binding
Biological Process
Renal Water Homeostasis
Renal Water Transport
Water Transport
Glycerol Transport
Cellular Response To Water Deprivation
Protein Homotetramerization
Transmembrane Transport
Cellular Response To Copper Ion
Cellular Response To Mercury Ion
Metanephric Collecting Duct Development
Response To Zinc Ion
Regulation Of Sequestering Of Zinc Ion
Positive Regulation Of Sequestering Of Zinc Ion
Zinc Ion Transmembrane Transport
Pathways
Vasopressin regulates renal water homeostasis via Aquaporins
Passive transport by Aquaporins
Zinc efflux and compartmentalization by the SLC30 family
Drugs
Diseases
Congenital nephrogenic diabetes insipidus (NDI)
GWAS
Allergic disease (asthma, hay fever or eczema) (
29083406
)
Allergic rhinitis (
30013184
)
Obsessive-compulsive disorder (
22889921
)
Interacting Genes
60 interacting genes:
ACTB
BCAP31
C4orf3
CCDC167
CDIPT
CERT1
CLCA4
CLDN7
CREB3
CREB3L1
CTSA
CXCL16
EEF1A1
EFNA5
ELL2
ERG28
ERGIC3
ERMP1
FAM209A
GPAA1
GPX8
IER3
IGFBP5
INSIG2
LEUTX
LHFPL5
MRM1
MS4A13
MUC1
NDFIP2
OLFM4
OR10AG1
PANX1
PDZK1IP1
PLP2
PNLIPRP1
RTP2
SLC26A6
SLC30A2
SLC38A7
SLC5A2
SNAP47
SNX5
SPCS1
SSR3
STUB1
STX8
SUPT20H
TM9SF2
TMEM109
TMEM218
TMEM230
TMEM236
TMEM60
TMEM86A
TMEM97
TRARG1
UBE2J1
VAPB
YIPF6
66 interacting genes:
ABHD16A
ADAM33
AQP2
AQP6
ATP13A1
C5orf46
CCL4
CCL4L2
CD40
CD52
CD79A
CD99L2
CPLX4
CREB3
CTSA
CYB561D2
EBAG9
EMP3
EVI2B
F11R
FAM174A
FDPS
FFAR2
FXYD3
FXYD6
GALNT15
GJA5
GJB2
GJB5
GLB1
GOLT1A
GPR161
GPR42
GPRC5D
HGFAC
KASH5
KCNN4
LMNA
LTA
LYVE1
MS4A13
NDUFAF1
NRM
OPRM1
PCNX2
PLPPR1
PVR
SEC22A
SELL
SERPING1
SLC10A6
SLC16A2
SLC18A1
SLC38A7
SLC39A2
SLC7A1
SLC7A8
TAS2R5
TM4SF18
TMEM107
TMEM52B
TMEM60
TMEM86A
TNFRSF12A
TRARG1
YIPF2
Entrez ID
359
7780
HPRD ID
00141
18057
Ensembl ID
ENSG00000167580
ENSG00000158014
Uniprot IDs
P41181
Q9BRI3
PDB IDs
4NEF
4OJ2
6QF5
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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