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AQP2 and CERT1
Data Source:
BioGRID
(two hybrid)
AQP2
CERT1
Description
aquaporin 2
ceramide transporter 1
Image
GO Annotations
Cellular Component
Golgi Apparatus
Plasma Membrane
Integral Component Of Plasma Membrane
Membrane
Integral Component Of Membrane
Basolateral Plasma Membrane
Apical Plasma Membrane
Transport Vesicle Membrane
Perinuclear Region Of Cytoplasm
Recycling Endosome
Extracellular Exosome
Lumenal Side Of Membrane
Nucleoplasm
Mitochondrion
Endoplasmic Reticulum Membrane
Golgi Apparatus
Cytosol
Membrane
Perinuclear Region Of Cytoplasm
Molecular Function
Water Transmembrane Transporter Activity
Protein Binding
Glycerol Transmembrane Transporter Activity
Water Channel Activity
Protein Binding
Kinase Activity
Phosphatidylinositol-4-phosphate Binding
Ceramide Binding
Ceramide Transfer Activity
Ceramide 1-phosphate Binding
Ceramide 1-phosphate Transfer Activity
Biological Process
Renal Water Homeostasis
Renal Water Transport
Water Transport
Glycerol Transport
Cellular Response To Water Deprivation
Protein Homotetramerization
Transmembrane Transport
Cellular Response To Copper Ion
Cellular Response To Mercury Ion
Metanephric Collecting Duct Development
Cell Morphogenesis
In Utero Embryonic Development
Heart Morphogenesis
Ceramide Metabolic Process
Muscle Contraction
Immune Response
Endoplasmic Reticulum Organization
Signal Transduction
Cell Population Proliferation
Phosphorylation
Sphingolipid Biosynthetic Process
Response To Endoplasmic Reticulum Stress
ER To Golgi Ceramide Transport
Ceramide Transport
Lipid Homeostasis
Mitochondrion Morphogenesis
Intermembrane Lipid Transfer
Intermembrane Sphingolipid Transfer
Ceramide 1-phosphate Transport
Pathways
Vasopressin regulates renal water homeostasis via Aquaporins
Passive transport by Aquaporins
Drugs
Diseases
Congenital nephrogenic diabetes insipidus (NDI)
GWAS
Allergic disease (asthma, hay fever or eczema) (
29083406
)
Allergic rhinitis (
30013184
)
Obsessive-compulsive disorder (
22889921
)
Interacting Genes
60 interacting genes:
ACTB
BCAP31
C4orf3
CCDC167
CDIPT
CERT1
CLCA4
CLDN7
CREB3
CREB3L1
CTSA
CXCL16
EEF1A1
EFNA5
ELL2
ERG28
ERGIC3
ERMP1
FAM209A
GPAA1
GPX8
IER3
IGFBP5
INSIG2
LEUTX
LHFPL5
MRM1
MS4A13
MUC1
NDFIP2
OLFM4
OR10AG1
PANX1
PDZK1IP1
PLP2
PNLIPRP1
RTP2
SLC26A6
SLC30A2
SLC38A7
SLC5A2
SNAP47
SNX5
SPCS1
SSR3
STUB1
STX8
SUPT20H
TM9SF2
TMEM109
TMEM218
TMEM230
TMEM236
TMEM60
TMEM86A
TMEM97
TRARG1
UBE2J1
VAPB
YIPF6
18 interacting genes:
ACTL8
AQP2
ARL6IP1
BSND
CBS
COL4A3
CSNK1G2
FTSJ1
ITGB3BP
MINAR1
PM20D2
POM121
REEP6
RTN3
RTN4
SMU1
STX2
TGM2
Entrez ID
359
10087
HPRD ID
00141
05246
Ensembl ID
ENSG00000167580
ENSG00000113163
Uniprot IDs
P41181
A0A024RAJ5
A0A2R8Y7C5
Q9Y5P4
PDB IDs
4NEF
4OJ2
6QF5
2E3M
2E3N
2E3O
2E3P
2E3Q
2E3R
2E3S
2RSG
2Z9Y
2Z9Z
3H3Q
3H3R
3H3S
3H3T
4HHV
5JJD
5ZYG
5ZYH
5ZYI
5ZYJ
5ZYK
5ZYL
5ZYM
6IEZ
6IF0
6J0O
6J81
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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