IL10RA and HACD1

Data Source:
BioGRID (two hybrid)

		IL10RA	HACD1
Description		interleukin 10 receptor subunit alpha	3-hydroxyacyl-CoA dehydratase 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Integral Component Of Membrane	Endoplasmic Reticulum Membrane Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Cytokine Receptor Activity Interleukin-10 Receptor Activity Protein Binding Interleukin-10 Binding Signaling Receptor Activity	Protein Binding 3-hydroxyacyl-CoA Dehydratase Activity Very-long-chain 3-hydroxyacyl-CoA Dehydratase Activity 3-hydroxy-arachidoyl-CoA Dehydratase Activity 3-hydroxy-behenoyl-CoA Dehydratase Activity 3-hydroxy-lignoceroyl-CoA Dehydratase Activity
	Biological Process	Negative Regulation Of Autophagy Cytokine-mediated Signaling Pathway Response To Lipopolysaccharide Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Regulation Of Synapse Organization Ubiquitin-dependent Endocytosis	Multicellular Organism Development Sphingolipid Biosynthetic Process Fatty Acid Elongation Long-chain Fatty-acyl-CoA Biosynthetic Process Very Long-chain Fatty Acid Biosynthetic Process
Pathways		Interleukin-10 signaling	Synthesis of very long-chain fatty acyl-CoAs
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Interacting Genes		20 interacting genes: BTRC C1QL4 CDS2 CMTM3 HACD1 IL10 IL10RB JAK1 MAL NIPAL4 PLPP6 RUSF1 SELENOK SLC38A7 SLC66A2 SLC7A14 SMCO4 TMEM242 TMUB2 YIPF6	7 interacting genes: CPLX4 IL10RA LMNA RNF170 TECR TMEM106C UBC
Entrez ID		3587	9200
HPRD ID		00911	10175
Ensembl ID		ENSG00000110324	ENSG00000165996
Uniprot IDs		Q13651	B0YJ81
PDB IDs		1J7V 1LQS 1Y6K 1Y6M 1Y6N 5IXI
Enriched GO Terms of Interacting Partners?
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