IL10RA and SLC7A14

Data Source:
BioGRID (two hybrid)

		IL10RA	SLC7A14
Description		interleukin 10 receptor subunit alpha	solute carrier family 7 member 14
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Integral Component Of Membrane	Nucleoplasm Lysosomal Membrane Cytosol Plasma Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Cytokine Receptor Activity Interleukin-10 Receptor Activity Protein Binding Interleukin-10 Binding Signaling Receptor Activity	Protein Binding Amino Acid Transmembrane Transporter Activity
	Biological Process	Negative Regulation Of Autophagy Cytokine-mediated Signaling Pathway Response To Lipopolysaccharide Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Regulation Of Synapse Organization Ubiquitin-dependent Endocytosis	Amino Acid Transmembrane Transport Amino Acid Transport Negative Regulation Of Phosphatase Activity
Pathways		Interleukin-10 signaling
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)	Obesity (extreme) ( 30677029) Spontaneous preterm birth without premature rupture of membranes ( 31194736)
Interacting Genes		20 interacting genes: BTRC C1QL4 CDS2 CMTM3 HACD1 IL10 IL10RB JAK1 MAL NIPAL4 PLPP6 RUSF1 SELENOK SLC38A7 SLC66A2 SLC7A14 SMCO4 TMEM242 TMUB2 YIPF6	47 interacting genes: ACSL5 ADGRE2 AGTRAP AIG1 APOL3 BET1 BNIP1 BNIP2 C1GALT1 CBLIF CCDC167 CCL4L2 CD53 CMTM5 DCBLD2 DERL1 EOGT ERMP1 FAM209A FAM20B FATE1 FCER1G FKBP7 IL10RA LINC00839 LTC4S MFF MGLL MMGT1 NINJ2 NSG1 PLPP6 PRB1 SCARF1 SCD SMCO4 TECR TMEM128 TMEM31 TRARG1 TREX1 UBIAD1 VAMP2 VKORC1 YIPF4 YIPF6 ZFPL1
Entrez ID		3587	57709
HPRD ID		00911	17222
Ensembl ID		ENSG00000110324	ENSG00000013293
Uniprot IDs		Q13651	Q8TBB6
PDB IDs		1J7V 1LQS 1Y6K 1Y6M 1Y6N 5IXI
Enriched GO Terms of Interacting Partners?
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