IGSF1 and INHBB

Data Source:
BioGRID (imaging technique)
HPRD (in vivo)

		IGSF1	INHBB
Description		immunoglobulin superfamily member 1	inhibin subunit beta B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Membrane Integral Component Of Membrane	Extracellular Region Extracellular Space Perinuclear Region Of Cytoplasm Cell Periphery
	Molecular Function	Protein Binding Coreceptor Activity Inhibin Binding Activin Receptor Antagonist Activity	Cytokine Activity Hormone Activity Protein Binding Growth Factor Activity Protein Homodimerization Activity Host Cell Surface Receptor Binding
	Biological Process	Regulation Of Transcription, DNA-templated Negative Regulation Of Activin Receptor Signaling Pathway	Ovarian Follicle Development Defense Response Cellular Response To Starvation Response To Wounding Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Cell Differentiation Negative Regulation Of Hepatocyte Growth Factor Production Cellular Response To Insulin Stimulus Activin Receptor Signaling Pathway Cellular Response To Leptin Stimulus Adhesion Of Symbiont To Host Cell Fat Cell Differentiation Negative Regulation Of Insulin Secretion Positive Regulation Of Follicle-stimulating Hormone Secretion Negative Regulation Of Follicle-stimulating Hormone Secretion Oocyte Development Positive Regulation Of Ovulation SMAD Protein Signal Transduction Positive Regulation Of Apoptotic Signaling Pathway
Pathways			Signaling by Activin Signaling by Activin Glycoprotein hormones Antagonism of Activin by Follistatin
Drugs
Diseases
GWAS		Age at voice drop ( 27182965) Menarche (age at onset) ( 27182965)	Age-related macular degeneration ( 23326517) Breast cancer ( 27117709) Breast cancer (estrogen-receptor negative) ( 27117709) Breast size ( 22747683 27182965) Obesity ( 21552555) Urate levels ( 31985003 23263486)
Interacting Genes		8 interacting genes: ACVR1 ACVR1B ACVR2A ACVR2B HECTD1 IGF1 INHBB RANBP10	12 interacting genes: ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B BMPR2 FNTA IGSF1 INHA INHBA INHBC TDGF1
Entrez ID		3547	3625
HPRD ID		02138	00934
Ensembl ID		ENSG00000147255	ENSG00000163083
Uniprot IDs		Q8N6C5	P09529
PDB IDs
Enriched GO Terms of Interacting Partners?
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