PLAC8 and PLAGL2

Data Source:
BioGRID (two hybrid)

		PLAC8	PLAGL2
Description		placenta associated 8	PLAG1 like zinc finger 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Azurophil Granule Lumen	Nucleus
	Molecular Function	Chromatin Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	Positive Regulation Of Cell Population Proliferation Response To Cold Negative Regulation Of Multicellular Organism Growth Defense Response To Bacterium Negative Regulation Of Apoptotic Process Neutrophil Degranulation Positive Regulation Of Transcription By RNA Polymerase II Brown Fat Cell Differentiation Positive Regulation Of Cold-induced Thermogenesis	Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Lipid Metabolic Process Post-embryonic Development Chylomicron Assembly Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways		Neutrophil degranulation
Drugs
Diseases
GWAS		QRS interval (sulfonylurea treatment interaction) ( 27958378)	Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Inflammatory bowel disease ( 28067908)
Interacting Genes		24 interacting genes: BAG4 C19orf54 COPS5 CYSRT1 FCHO1 KRTAP12-2 KRTAP19-1 KRTAP19-6 LCE1A LCE1C LCE2B LCE5A MEOX2 PLAGL2 PPP3CA RBPMS RHOXF2 TEX37 TRAF1 TRIP13 UBAP2 USP54 VAMP5 WWOX	44 interacting genes: ANKRD11 ARID5A BCAS2 CATSPER1 CCDC120 CTNNA3 DAPP1 DHX57 DVL3 FAM161B FAM83A FAM90A1 GEM GLYCTK GPATCH2L GYS1 INO80B IRX2 KANK2 MAD2L2 MAPK1 MORN4 NOS1AP OIP5 OLIG3 PAX9 PHC2 PIN1 PLAC8 PRR35 RCHY1 RHOBTB3 RIPPLY1 SAMD11 SEPHS1 SMARCD1 TEKT3 TEKT4 TRAF4 TRIM41 VEZF1 YPEL5 ZNF564 ZNF581
Entrez ID		51316	5326
HPRD ID		06335	05333
Ensembl ID		ENSG00000145287	ENSG00000126003
Uniprot IDs		Q9NZF1 X2BQ60	Q9UPG8
PDB IDs
Enriched GO Terms of Interacting Partners?
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