LCE3C and KRTAP5-3

Data Source:
BioGRID (two hybrid)

		LCE3C	KRTAP5-3
Description		late cornified envelope 3C	keratin associated protein 5-3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Cytosol Keratin Filament
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Keratinization Killing Of Cells Of Other Organism Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium	Keratinization
Pathways		Formation of the cornified envelope	Keratinization
Drugs			Beta-D-Glucose
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011)
Interacting Genes		55 interacting genes: ADAMTSL4 ALPP CHIC2 CYP21A2 CYSRT1 EFEMP2 GRN HOXA1 KPRP KRT31 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-3 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP3-2 KRTAP3-3 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-4 LCE1B MDFI NBPF19 NOTCH2NLA PCSK5 PLSCR1 RGS17 RGS20 SPRY1 SPRY2 TRIM42 TSPAN4 ZNF655	43 interacting genes: ADAMTSL4 CATSPER1 CRCT1 CYSRT1 ECM1 FBXO34 FUCA2 GLRX3 HOXA1 KPRP KRTAP1-3 KRTAP1-5 KRTAP10-8 KRTAP11-1 KRTAP15-1 KRTAP4-2 KRTAP5-1 KRTAP5-9 KRTAP9-2 KRTAP9-3 LCE1A LCE1B LCE1C LCE1D LCE1F LCE2C LCE3A LCE3C LCE3D LCE3E LCE4A LCE5A LELP1 MEOX2 NBPF19 NOTCH2NLA NR4A3 NUFIP2 OTX1 POU4F2 RAMP3 RGS17 SMCP
Entrez ID		353144	387266
HPRD ID		17262	12395
Ensembl ID		ENSG00000244057	ENSG00000196224
Uniprot IDs		Q5T5A8	Q6L8H2
PDB IDs
Enriched GO Terms of Interacting Partners?
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