LCE1D and AMOT

Data Source:
BioGRID (two hybrid)

		LCE1D	AMOT
Description		late cornified envelope 1D	angiomotin
Image		No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Cytoplasm Perinuclear Region Of Cytoplasm	Ruffle Nucleoplasm Cytosol Actin Filament Plasma Membrane Bicellular Tight Junction COP9 Signalosome External Side Of Plasma Membrane Lamellipodium Cell Junction Endocytic Vesicle Cytoplasmic Vesicle
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding Signaling Receptor Activity Angiostatin Binding
	Biological Process	Keratinization Cognition Cellular Response To Calcium Ion	Angiogenesis Vasculogenesis In Utero Embryonic Development Gastrulation With Mouth Forming Second Establishment Of Cell Polarity Involved In Ameboidal Cell Migration Chemotaxis Negative Regulation Of Angiogenesis Actin Cytoskeleton Organization Regulation Of Cell Migration Negative Regulation Of GTPase Activity Cellular Protein Localization Hippo Signaling Positive Regulation Of Embryonic Development Cell Migration Involved In Gastrulation Blood Vessel Endothelial Cell Migration Regulation Of Small GTPase Mediated Signal Transduction
Pathways		Formation of the cornified envelope
Drugs
Diseases
GWAS		Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011)
Interacting Genes		57 interacting genes: ALPP AMOT CATSPER1 CYSRT1 GRN HOXA1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-11 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP2-3 KRTAP2-4 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1B LCE1C LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3B MACO1 MDFI MEOX2 NBPF19 NOTCH2NLA NTAQ1 PCSK5 PIAS4 RAD54L2 RGS17 RNF4 SCARF1 SMCP SPRY1 TGFB1 TRIM42 UBE2I	60 interacting genes: ACTA1 AMOTL2 AP1M1 APP AQP1 AXIN2 C1orf216 CAPN3 DISC1 FHL2 HOXA1 HPCAL1 KIAA1328 KRT14 KRT15 KRT16 KRT19 KRT24 KRT27 KRT31 KRT34 KRT36 KRT75 LCE1D LMNB2 LMO4 LURAP1 LZTS1 MAGEA4 MAGI1 MAPK3 MED4 MEOX2 MIS18A MYBPC1 MYBPC2 MYOM3 NEDD4 NEDD4L NF2 NTAQ1 NUFIP2 PBLD PIBF1 PIK3C2A PIN1 PLG PRKAA2 PTEN PTPA PTPN14 RBM48 SEPTIN1 SLIRP SMC1A SNAPC5 SOCS6 THRA TTN UNC119
Entrez ID		353134	154796
HPRD ID		13968	02327
Ensembl ID		ENSG00000172155	ENSG00000126016
Uniprot IDs		Q5T752	Q4VCS5
PDB IDs			6JJX
Enriched GO Terms of Interacting Partners?
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