AMOT and MYBPC1

Data Source:
BioGRID (two hybrid)

		AMOT	MYBPC1
Description		angiomotin	myosin binding protein C1
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GO Annotations	Cellular Component	Ruffle Nucleoplasm Cytosol Actin Filament Plasma Membrane Bicellular Tight Junction COP9 Signalosome External Side Of Plasma Membrane Lamellipodium Cell Junction Endocytic Vesicle Cytoplasmic Vesicle	Cytosol Myofibril Myosin Filament
	Molecular Function	Protein Binding Signaling Receptor Activity Angiostatin Binding	Actin Binding Protein Binding Structural Constituent Of Muscle Myosin Binding Titin Binding
	Biological Process	Angiogenesis Vasculogenesis In Utero Embryonic Development Gastrulation With Mouth Forming Second Establishment Of Cell Polarity Involved In Ameboidal Cell Migration Chemotaxis Negative Regulation Of Angiogenesis Actin Cytoskeleton Organization Regulation Of Cell Migration Negative Regulation Of GTPase Activity Cellular Protein Localization Hippo Signaling Positive Regulation Of Embryonic Development Cell Migration Involved In Gastrulation Blood Vessel Endothelial Cell Migration Regulation Of Small GTPase Mediated Signal Transduction	Cell Adhesion Muscle Filament Sliding
Pathways			Striated Muscle Contraction
Drugs
Diseases
GWAS			Blood protein levels ( 28240269) Lung function (FEV1) ( 24023788) Memory decline ( 31985465)
Interacting Genes		60 interacting genes: ACTA1 AMOTL2 AP1M1 APP AQP1 AXIN2 C1orf216 CAPN3 DISC1 FHL2 HOXA1 HPCAL1 KIAA1328 KRT14 KRT15 KRT16 KRT19 KRT24 KRT27 KRT31 KRT34 KRT36 KRT75 LCE1D LMNB2 LMO4 LURAP1 LZTS1 MAGEA4 MAGI1 MAPK3 MED4 MEOX2 MIS18A MYBPC1 MYBPC2 MYOM3 NEDD4 NEDD4L NF2 NTAQ1 NUFIP2 PBLD PIBF1 PIK3C2A PIN1 PLG PRKAA2 PTEN PTPA PTPN14 RBM48 SEPTIN1 SLIRP SMC1A SNAPC5 SOCS6 THRA TTN UNC119	23 interacting genes: ACO1 AMOT ANKRD1 ASH2L C1QTNF9 CALM1 CAPN3 CLIP4 DNAJB5 DNAJB6 DYSF FHL1 FHL2 FHL3 KLHL41 MEOX2 MYBPC2 NCF1 RAF1 SGCG TRIM55 TRIM63 TTN
Entrez ID		154796	4604
HPRD ID		02327	01185
Ensembl ID		ENSG00000126016	ENSG00000196091
Uniprot IDs		Q4VCS5	A8KAB1 B3KPP3 Q00872 Q86TA8
PDB IDs		6JJX	1X44 2DAV 2YUV 2YUW 2YUX 2YUZ 2YXM
Enriched GO Terms of Interacting Partners?
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