LCE1A and PLAC8

Data Source:
BioGRID (two hybrid)

		LCE1A	PLAC8
Description		late cornified envelope 1A	placenta associated 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol	Extracellular Region Azurophil Granule Lumen
	Molecular Function	Protein Binding	Chromatin Binding
	Biological Process	Cornification	Positive Regulation Of Cell Population Proliferation Response To Cold Negative Regulation Of Multicellular Organism Growth Defense Response To Bacterium Negative Regulation Of Apoptotic Process Neutrophil Degranulation Positive Regulation Of Transcription By RNA Polymerase II Brown Fat Cell Differentiation Positive Regulation Of Cold-induced Thermogenesis
Pathways		Formation of the cornified envelope	Neutrophil degranulation
Drugs
Diseases
GWAS		Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011)	QRS interval (sulfonylurea treatment interaction) ( 27958378)
Interacting Genes		69 interacting genes: ADAMTSL4 AQP1 CCN3 CFP CHIC2 CYSRT1 EFEMP2 FBLN1 FUCA2 GRN HOXA1 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP12-2 KRTAP12-3 KRTAP12-4 KRTAP21-2 KRTAP3-2 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1B LCE1C LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE4A LCE5A MDFI MESD NBPF19 NID2 NOTCH2NLA PLA2G10 PLAC8 PLSCR2 PLSCR4 RGS17 RGS20 SLC39A7 SMCP SPRY1 SPRY2 SPRY3 TGFB1 TRIM42 TSPAN4 VWC2 VWC2L	24 interacting genes: BAG4 C19orf54 COPS5 CYSRT1 FCHO1 KRTAP12-2 KRTAP19-1 KRTAP19-6 LCE1A LCE1C LCE2B LCE5A MEOX2 PLAGL2 PPP3CA RBPMS RHOXF2 TEX37 TRAF1 TRIP13 UBAP2 USP54 VAMP5 WWOX
Entrez ID		353131	51316
HPRD ID		13966	06335
Ensembl ID		ENSG00000186844	ENSG00000145287
Uniprot IDs		Q5T7P2	Q9NZF1 X2BQ60
PDB IDs
Enriched GO Terms of Interacting Partners?
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