APRT and TTC19

Data Source:
BioGRID (two hybrid)

		APRT	TTC19
Description		adenine phosphoribosyltransferase	tetratricopeptide repeat domain 19
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleoplasm Cytoplasm Cytosol Secretory Granule Lumen Extracellular Exosome	Mitochondrion Mitochondrial Inner Membrane Centrosome Midbody Respirasome
	Molecular Function	Adenine Binding Adenine Phosphoribosyltransferase Activity Protein Binding AMP Binding	Protein Binding
	Biological Process	Purine Ribonucleoside Salvage Adenine Salvage Lactation Grooming Behavior Cellular Response To Insulin Stimulus Purine-containing Compound Salvage Neutrophil Degranulation AMP Salvage	Mitotic Cytokinesis Mitochondrial Respiratory Chain Complex III Assembly
Pathways		Neutrophil degranulation Purine salvage
Drugs		Adenine 5-O-phosphono-alpha-D-ribofuranosyl diphosphate 9-Deazaadenine Citric acid
Diseases		Adenine phosphoribosyltransferase deficiency; 2,8-Dihydroxyadenine urolithiasis	Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS		Hair color ( 26926045)
Interacting Genes		5 interacting genes: APP IKBKG MLH1 SUMO2 TTC19	44 interacting genes: AGXT APRT ATXN1 C20orf85 CCDC33 CHMP4A COA6 CYSLTR2 DMRT3 EIF4ENIF1 FAM136A FAM217B FH FTO GORASP2 GPANK1 HOXD12 HPS6 IHO1 L3MBTL3 LDB2 MLN MXRA8 NAB2 NME4 POU6F2 PRR35 RBP1 REL RUSC1 RXFP3 SH2D4A SHISA6 SLC22A18AS SMG9 SPRED1 TBX2 TCAP UBA1 UPF3B USP20 USP54 WASHC1 ZNF688
Entrez ID		353	54902
HPRD ID		00029	07899
Ensembl ID		ENSG00000198931	ENSG00000011295
Uniprot IDs		P07741	A0A024RD83 Q6DKK2
PDB IDs		1OPU 1ORE 1ZN7 1ZN8 1ZN9 4X44 4X45 6FCH 6FCI 6FCL 6FD4 6FD5 6FD6 6HGP 6HGQ 6HGR 6HGS
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?