TTC19 and RXFP3

Data Source:
BioGRID (two hybrid)

		TTC19	RXFP3
Description		tetratricopeptide repeat domain 19	relaxin family peptide receptor 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Centrosome Midbody Respirasome	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Protein Binding	G Protein-coupled Receptor Activity G Protein-coupled Peptide Receptor Activity
	Biological Process	Mitotic Cytokinesis Mitochondrial Respiratory Chain Complex III Assembly	G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Positive Regulation Of Cytokinesis
Pathways			G alpha (i) signalling events Relaxin receptors
Drugs
Diseases		Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS
Interacting Genes		44 interacting genes: AGXT APRT ATXN1 C20orf85 CCDC33 CHMP4A COA6 CYSLTR2 DMRT3 EIF4ENIF1 FAM136A FAM217B FH FTO GORASP2 GPANK1 HOXD12 HPS6 IHO1 L3MBTL3 LDB2 MLN MXRA8 NAB2 NME4 POU6F2 PRR35 RBP1 REL RUSC1 RXFP3 SH2D4A SHISA6 SLC22A18AS SMG9 SPRED1 TBX2 TCAP UBA1 UPF3B USP20 USP54 WASHC1 ZNF688	10 interacting genes: APP ENO1 GNAS HSP90B1 KATNB1 NCKIPSD RLN3 TMEM248 TTC19 YWHAE
Entrez ID		54902	51289
HPRD ID		07899	17979
Ensembl ID		ENSG00000011295	ENSG00000182631
Uniprot IDs		A0A024RD83 Q6DKK2	Q9NSD7
PDB IDs
Enriched GO Terms of Interacting Partners?
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