TTC19 and HPS6

Data Source:
BioGRID (two hybrid)

		TTC19	HPS6
Description		tetratricopeptide repeat domain 19	HPS6 biogenesis of lysosomal organelles complex 2 subunit 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Centrosome Midbody Respirasome	Lysosomal Membrane Endoplasmic Reticulum Membrane BLOC-2 Complex Early Endosome Membrane
	Molecular Function	Protein Binding	Protein Binding GTP-dependent Protein Binding Small GTPase Binding
	Biological Process	Mitotic Cytokinesis Mitochondrial Respiratory Chain Complex III Assembly	Organelle Organization Blood Coagulation Melanocyte Differentiation Lysosome Localization Protein Localization To Membrane
Pathways
Drugs
Diseases		Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome	Hermansky-Pudlak syndrome (HPS)
GWAS			Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435)
Interacting Genes		44 interacting genes: AGXT APRT ATXN1 C20orf85 CCDC33 CHMP4A COA6 CYSLTR2 DMRT3 EIF4ENIF1 FAM136A FAM217B FH FTO GORASP2 GPANK1 HOXD12 HPS6 IHO1 L3MBTL3 LDB2 MLN MXRA8 NAB2 NME4 POU6F2 PRR35 RBP1 REL RUSC1 RXFP3 SH2D4A SHISA6 SLC22A18AS SMG9 SPRED1 TBX2 TCAP UBA1 UPF3B USP20 USP54 WASHC1 ZNF688	10 interacting genes: CREB1 EP300 HPS5 MARK4 MNAT1 OSGEP PIK3CB PUM3 SUMO2 TTC19
Entrez ID		54902	79803
HPRD ID		07899	08471
Ensembl ID		ENSG00000011295	ENSG00000166189
Uniprot IDs		A0A024RD83 Q6DKK2	Q86YV9
PDB IDs
Enriched GO Terms of Interacting Partners?
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