IGH and NR1I3

Data Source:
BioGRID (two hybrid)

		IGH	NR1I3
Description		immunoglobulin heavy locus	nuclear receptor subfamily 1 group I member 3
Image		No pdb structure
GO Annotations	Cellular Component		Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton
	Molecular Function		RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Nuclear Receptor Activity Protein Binding Zinc Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process		Negative Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Signal Transduction Cell Differentiation Intracellular Receptor Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs			Doxylamine Meclizine Loperamide Ketoconazole Atorvastatin Pheniramine Prasterone 16,17-Androstene-3-Ol Resveratrol Cholesterol Phenolphthalein 3,20-Pregnanedione Hexestrol Triclosan
Diseases
GWAS		Alzheimer's disease (late onset) ( 24162737) Baseline cortisol levels in response to low dose short synacthen test in corticosteroid treated asthma ( 29551627) IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis) ( 28878392) IgG fucosylation phenotypes (multivariate analysis) ( 28878392) IgG galactosylation phenotypes (multivariate analysis) ( 28878392) IgG monogalactosylation phenotypes (multivariate analysis) ( 28878392) IgG monosialylation phenotypes (multivariate analysis) ( 28878392) IgG N-glycosylation phenotypes (multivariate analysis) ( 28878392) IgG sialylation phenotypes (multivariate analysis) ( 28878392)	Blood metabolite levels ( 24816252)
Interacting Genes		2 interacting genes: FBXO2 NR1I3	18 interacting genes: CHD9 DNMT3L FTH1 HNF4A IGH MAP4 MED1 NCOA1 NCOA3 NR0B2 POU1F1 PPARGC1A PSMC4 PSMC5 RXRA SNRPD3 SNX13 SRC
Entrez ID		3492	9970
HPRD ID			04858
Ensembl ID			ENSG00000143257
Uniprot IDs			F1DAL4 Q14994
PDB IDs			1XV9 1XVP
Enriched GO Terms of Interacting Partners?
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