APOC4 and APOL2

  • Data Source:
  • BioGRID (two hybrid)

APOC4

APOL2

Description apolipoprotein C4 apolipoprotein L2
Image No pdb structure No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease (onset between ages 58 and 79) ( 30979435)
  • Alzheimer's disease or HDL levels (pleiotropy) ( 30805717)
  • Apolipoprotein A1 levels ( 32203549)
  • Blood protein levels ( 29875488 28240269)
  • Carotid intima media thickness (maximum) ( 31801372)
  • Carotid intima media thickness (mean) ( 31801372)
  • Cerebrospinal AB1-42 levels in Alzheimer's disease dementia ( 29274321)
  • Cerebrospinal AB1-42 levels in mild cognitive impairment ( 29274321)
  • Cerebrospinal AB1-42 levels in normal cognition ( 29274321)
  • Cerebrospinal fluid AB1-42 levels ( 29274321)
  • Cerebrospinal fluid p-tau levels ( 29274321)
  • Cerebrospinal fluid p-tau levels in mild cognitive impairment ( 29274321)
  • Cerebrospinal fluid t-tau levels ( 29274321)
  • Cerebrospinal fluid t-tau levels in mild cognitive impairment ( 29274321)
  • HDL cholesterol levels ( 32203549)
  • Hippocampal volume ( 29274321)
  • Hippocampal volume in Alzheimer's disease dementia ( 29274321)
  • LDL cholesterol ( 18802019 18193043 18193044 20864672 19060906)
  • Logical memory (delayed recall) ( 29274321)
  • Logical memory (immediate recall) ( 29274321)
  • Quantitative traits ( 19197348)
  • Very long-chain saturated fatty acid levels (fatty acid 20:0) ( 25378659)
  • Epigenetic age acceleration in alcohol use disorder ( 31466081)
Interacting Genes 24 interacting genes: APOL2 BCL2L2 DIABLO GAD2 GSDMA IFI27 LETMD1 MAIP1 MICOS10 MICOS13 NFU1 PORCN RSAD2 SENP2 SNAP47 SYT16 TBC1D20 THBD TIMMDC1 TMEM14B TPRG1 UBQLN1 UBQLN2 VKORC1 33 interacting genes: AIG1 APOC2 APOC4 AR BSND CISD2 CYBC1 EBAG9 EMP1 FAM209A GET1 GJB5 ITGB2 KCNA1 LMNA MARCHF3 MFF MGST3 PANX1 PSCA SFXN5 SIT1 SLC18A1 SLC26A6 STX1A STX2 TMED8 TMEM139 TMEM45B TMEM52B TMEM60 USE1 YIPF6
Entrez ID 346 23780
HPRD ID 02848 06263
Ensembl ID ENSG00000267467 ENSG00000128335
Uniprot IDs P55056 A0A024R1M8 J3KQL8 Q9BQE5
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?