ICAM3 and RFX2

Data Source:
BioGRID (affinity chromatography technology)

		ICAM3	RFX2
Description		intercellular adhesion molecule 3	regulatory factor X2
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Extracellular Exosome	Chromatin Nucleus Cytoplasm
	Molecular Function	Signaling Receptor Binding Integrin Binding Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Stimulatory C-type Lectin Receptor Signaling Pathway Phagocytosis Cell Adhesion Extracellular Matrix Organization Regulation Of Immune Response Cell-cell Adhesion	Acrosome Assembly Regulation Of Transcription By RNA Polymerase II Spermatid Development Cilium Assembly
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Integrin cell surface interactions CD209 (DC-SIGN) signaling
Drugs
Diseases
GWAS		Crohn's disease ( 28067908 21102463) Inflammatory bowel disease ( 28067908) Rheumatoid arthritis ( 23143596) Rheumatoid arthritis (ACPA-positive) ( 23143596) Systemic lupus erythematosus or rheumatoid arthritis ( 27193031)	Heel bone mineral density ( 30598549) Mean platelet volume ( 32888494 27863252) Platelet distribution width ( 32888494)
Interacting Genes		20 interacting genes: APP BRICD5 CD209 CLDN19 CLDN4 CLEC4M EDDM3B EZR ITGAD ITGAL ITGB2 MSN NINJ2 PRKCQ SEC22A SFTPC SMCO4 SMIM1 TSPO ZBTB16	10 interacting genes: C1orf94 EYA2 FOXJ1 FOXN4 MDFI NFKBID PIAS2 RFX1 RFX4 RFX6
Entrez ID		3385	5990
HPRD ID		00889	00824
Ensembl ID		ENSG00000076662	ENSG00000087903
Uniprot IDs		A0A024R7C1 K7ERN2 P32942	P48378
PDB IDs		1T0P
Enriched GO Terms of Interacting Partners?
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