KRTAP19-5 and PRKAG3

Data Source:
BioGRID (two hybrid)

		KRTAP19-5	PRKAG3
Description		keratin associated protein 19-5	protein kinase AMP-activated non-catalytic subunit gamma 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament	Extracellular Space Nucleus Nucleoplasm Cytoplasm Cytosol Nucleotide-activated Protein Kinase Complex
	Molecular Function	Protein Binding	Protein Binding ATP Binding AMP Binding Protein Kinase Regulator Activity Protein Kinase Binding
	Biological Process	Keratinization	Glycogen Biosynthetic Process Glycolytic Process Protein Phosphorylation Fatty Acid Biosynthetic Process Cell Cycle Arrest Response To Muscle Activity Involved In Regulation Of Muscle Adaptation Macroautophagy Regulation Of Macroautophagy Intracellular Signal Transduction Cellular Response To Glucose Starvation Regulation Of Catalytic Activity Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Signal Transduction By P53 Class Mediator
Pathways		Keratinization	Translocation of SLC2A4 (GLUT4) to the plasma membrane Macroautophagy Activation of PPARGC1A (PGC-1alpha) by phosphorylation Energy dependent regulation of mTOR by LKB1-AMPK TP53 Regulates Metabolic Genes Regulation of TP53 Activity through Phosphorylation Lipophagy Activation of AMPK downstream of NMDARs
Drugs			Adenosine phosphate Acetylsalicylic acid Fostamatinib
Diseases
GWAS			Apolipoprotein A1 levels ( 32203549) HDL cholesterol ( 25961943) HDL cholesterol levels ( 32203549) Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Male-pattern baldness ( 28196072) Monocyte count ( 32888494) Triglyceride levels ( 32203549)
Interacting Genes		97 interacting genes: ANKHD1 APOBEC1 ARID5A ATN1 ATPAF2 BHLHE40 C11orf16 C9orf24 CAMK2A CAMK2B CATSPER1 CCDC17 CELF5 CHRD COL8A1 CRACR2A CREB5 CRYAB CYSRT1 DAB1 DAZAP2 DMRT3 DMRTB1 EFEMP2 ENKD1 ESRP1 EVX2 FAM168A FAM214B GLIS2 GLYCTK GPANK1 GRINA GUCD1 HAPLN2 HGS HOXB9 HYPK INCA1 KIFC3 KPRP KRT34 KRTAP12-4 KRTAP15-1 KRTAP6-2 KRTAP6-3 KRTAP8-1 MAGED1 MAPK1IP1L MGAT5B MYOZ3 MYPOP OIP5 OLIG3 OXER1 P4HA3 PATZ1 PITX1 PITX2 PLSCR4 POU2AF1 PPP1R16A PPP1R32 PRKAG3 PRPF31 PRR13 PRR20A PRR20B PRR20C PRR20D PRR20E PSMA3 PSMB2 PSMB4 RBPMS RBPMS2 RHOXF2 RNF38 RNF44 RTP5 RUSC1 SEMA3B SNRPC SOHLH1 TCF7L2 TEKT3 TEX37 TLE5 TNIP1 TSPYL6 UBQLN2 VAC14 VEZF1 VPS37C ZBTB32 ZIC1 ZNF414	6 interacting genes: BRCA1 CRYAB KRTAP19-5 LMCD1 NGRN PRKAA1
Entrez ID		337972	53632
HPRD ID		11209	16085
Ensembl ID		ENSG00000186977	ENSG00000115592
Uniprot IDs		Q3LI72	Q9UGI9
PDB IDs
Enriched GO Terms of Interacting Partners?
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