ESR2 and PPARGC1A

  • Data Source:
  • BioGRID (two hybrid)
  • HPRD (in vivo, in vitro, two hybrid)

ESR2

PPARGC1A

Description estrogen receptor 2 PPARG coactivator 1 alpha
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Atrial fibrillation ( 30061737)
  • Chronotype ( 30696823)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Depression ( 29700475)
  • Hematocrit ( 32888494 27863252)
  • Hemoglobin ( 32888494)
  • Hemoglobin concentration ( 27863252)
  • Hemoglobin levels ( 32327693)
  • Metabolite levels ( 23823483)
  • Prostate cancer ( 26443449)
  • Red blood cell count ( 32888494 27863252)
  • Coffee consumption ( 31046077)
  • Cognitive decline rate in late mild cognitive impairment ( 26252872)
  • Corneal astigmatism ( 29422769)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Essential tremor ( 27797806)
  • Estimated glomerular filtration rate ( 31152163 31015462)
  • Hematocrit ( 32888494)
  • Hemoglobin ( 32888494)
  • Lead levels ( 26025379)
  • Molar-incisor hypomineralization ( 23918034)
  • PR interval ( 32439900)
  • Refractive error ( 32231278)
  • Resting heart rate ( 27798624)
  • Rosacea symptom severity ( 29771307)
  • Schizophrenia ( 30285260)
  • Subjective response to placebo treatment in childhood asthma (change in cough/wheeze) ( 31557306)
  • Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
Interacting Genes 104 interacting genes: AGR3 AKAP13 AKT1 ARID5A BCAS2 CALM1 CALM2 CALM3 CASC3 CASZ1 CCNC CDK8 CYSRT1 DAP3 DDX54 DKK3 DNMT3L DNTTIP2 EP300 ESR1 HOXA1 IL13RA2 IL24 ITIH5 JMJD1C KAT5 KLK9 KPNA3 KPRP KRTAP6-2 LCK LRATD2 MAD2L1 MAPK1 MAPK11 MED1 MED10 MED12 MED14 MED16 MED17 MED20 MED21 MED23 MED24 MED6 MED7 MEOX2 MKNK2 MMS19 MRC2 MSH2 NCOA1 NCOA2 NCOA3 NCOA6 NCOA7 NCOR1 NCOR2 NFKBIB NFKBID NOTCH2NLA NR0B1 NR0B2 NRIP1 OXT PELP1 PIAS1 PIAS2 PIAS3 PLSCR1 PNRC1 PNRC2 PPARGC1A PPP5C PRMT2 PRSS50 PSMC3IP PSMC5 RBFOX2 RBM39 REXO4 RFX6 SERPINH1 SMAD2 SMAD3 SMAD4 SMARCE1 SP1 SRA1 SRC SREBF1 STAT5A TFF1 TRAM1 TRIM24 TRIM59 TRIP4 TXNRD1 WIPI1 YWHAH YWHAQ ZBTB17 ZNHIT3 43 interacting genes: CAPNS1 CDK6 CREBBP ESR1 ESR2 ESRRA ESRRG FBXW7 GSK3B HCFC1 HNF4A LRPPRC MAPK14 MED1 MED12 MED14 MED17 MYBBP1A NCL NCOA1 NCOA6 NDN NR1H4 NR1I2 NR1I3 NR3C1 NRF1 PPARA PPARD PPARG RARB RXRA SIRT1 SKP1 SRSF4 SRSF5 SRSF6 THRB TP53 UBC UBE2I USF1 USF2
Entrez ID 2100 10891
HPRD ID 03390 05155
Ensembl ID ENSG00000140009 ENSG00000109819
Uniprot IDs A0A348FV93 F1D8N3 Q0PTK2 Q7LCB3 Q92731 A0A024R9Q9 Q9UBK2
PDB IDs 1L2J 1NDE 1QKM 1U3Q 1U3R 1U3S 1U9E 1X76 1X78 1X7B 1X7J 1YY4 1YYE 1ZAF 2FSZ 2GIU 2I0G 2JJ3 2NV7 2QTU 2YJD 2YLY 2Z4B 3OLL 3OLS 3OMO 3OMP 3OMQ 4J24 4J26 4ZI1 5TOA 1XB7 3B1M 3CS8 3D24 3U9Q 3V9T 3V9V 4QJR 4QK4 5Q0I 5TWO 5UNJ 5Z5S 5Z6S 6AD9 6FZF 6FZP 6IZM 6IZN 6K0T 6KXX 6KXY 6LN4 6MS7 6NWK 6NWL 6W9K 6W9L
Enriched GO Terms of Interacting Partners?
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