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HUS1 and RAD17
Data Source:
HPRD
(in vivo)
HUS1
RAD17
Description
HUS1 checkpoint clamp component
RAD17 checkpoint clamp loader component
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Cytosol
Checkpoint Clamp Complex
Site Of Double-strand Break
Chromosome, Telomeric Region
Nucleus
Nucleoplasm
Nucleolus
Rad17 RFC-like Complex
Molecular Function
Protein Binding
Chromatin Binding
DNA Clamp Loader Activity
Protein Binding
ATP Binding
Biological Process
DNA Damage Checkpoint
Telomere Maintenance
Double-strand Break Repair Via Homologous Recombination
Regulation Of Protein Phosphorylation
DNA Replication
DNA Repair
Nucleotide-excision Repair
Protein Phosphorylation
Cellular Response To DNA Damage Stimulus
Response To UV
Embryo Development Ending In Birth Or Egg Hatching
Intra-S DNA Damage Checkpoint
Mitotic DNA Replication Checkpoint
Meiotic DNA Integrity Checkpoint
Cellular Response To Ionizing Radiation
Regulation Of Signal Transduction By P53 Class Mediator
DNA Replication Checkpoint
DNA Damage Checkpoint
DNA Replication
DNA Repair
Cellular Response To DNA Damage Stimulus
Negative Regulation Of DNA Replication
Intra-S DNA Damage Checkpoint
Mitotic DNA Replication Checkpoint
Regulation Of Phosphorylation
Regulation Of Signal Transduction By P53 Class Mediator
Pathways
Activation of ATR in response to replication stress
HDR through Single Strand Annealing (SSA)
Processing of DNA double-strand break ends
Presynaptic phase of homologous DNA pairing and strand exchange
Regulation of TP53 Activity through Phosphorylation
G2/M DNA damage checkpoint
Activation of ATR in response to replication stress
HDR through Single Strand Annealing (SSA)
Processing of DNA double-strand break ends
Presynaptic phase of homologous DNA pairing and strand exchange
Regulation of TP53 Activity through Phosphorylation
G2/M DNA damage checkpoint
Drugs
Diseases
GWAS
Gut microbiota alpha diversity (Shannon index) (
33208821
)
Obstructive sleep apnea during REM sleep (apnea hypopnea index) (
29077507
)
Blood urea nitrogen levels (
31152163
)
Interacting Genes
28 interacting genes:
C4orf46
CD200
DCUN1D5
DNAJC7
FEN1
GRIP1
HDAC1
HUS1B
MSH2
MSH3
MSH6
NEIL1
NTAQ1
OGG1
PCNA
POLB
RAD1
RAD17
RAD9A
RAD9B
RHNO1
RPA1
RPA2
SDCBP
SIRT6
TDG
TOPBP1
YWHAQ
15 interacting genes:
ATM
ATR
HUS1
MCM7
POLE
PRKDC
PRMT6
RAD1
RAD9A
RAD9B
RFC2
RFC3
RFC4
SNU13
USP20
Entrez ID
3364
5884
HPRD ID
04787
09124
Ensembl ID
ENSG00000136273
ENSG00000152942
Uniprot IDs
A4D2F2
O60921
O75943
PDB IDs
3A1J
3G65
3GGR
6J8Y
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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