HUS1 and RAD9B

Data Source:
HPRD (in vivo)

		HUS1	RAD9B
Description		HUS1 checkpoint clamp component	RAD9 checkpoint clamp component B
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytosol Checkpoint Clamp Complex Site Of Double-strand Break	Nucleus Nucleoplasm Checkpoint Clamp Complex
	Molecular Function	Protein Binding	Protein Binding 3'-5' Exonuclease Activity
	Biological Process	DNA Damage Checkpoint Telomere Maintenance Double-strand Break Repair Via Homologous Recombination Regulation Of Protein Phosphorylation DNA Replication DNA Repair Nucleotide-excision Repair Protein Phosphorylation Cellular Response To DNA Damage Stimulus Response To UV Embryo Development Ending In Birth Or Egg Hatching Intra-S DNA Damage Checkpoint Mitotic DNA Replication Checkpoint Meiotic DNA Integrity Checkpoint Cellular Response To Ionizing Radiation Regulation Of Signal Transduction By P53 Class Mediator	DNA Replication Checkpoint DNA Replication DNA Repair Intra-S DNA Damage Checkpoint Cellular Response To Ionizing Radiation Nucleic Acid Phosphodiester Bond Hydrolysis Regulation Of Signal Transduction By P53 Class Mediator
Pathways		Activation of ATR in response to replication stress HDR through Single Strand Annealing (SSA) Processing of DNA double-strand break ends Presynaptic phase of homologous DNA pairing and strand exchange Regulation of TP53 Activity through Phosphorylation G2/M DNA damage checkpoint	Activation of ATR in response to replication stress HDR through Single Strand Annealing (SSA) Processing of DNA double-strand break ends Presynaptic phase of homologous DNA pairing and strand exchange Regulation of TP53 Activity through Phosphorylation G2/M DNA damage checkpoint
Drugs
Diseases
GWAS		Gut microbiota alpha diversity (Shannon index) ( 33208821) Obstructive sleep apnea during REM sleep (apnea hypopnea index) ( 29077507)
Interacting Genes		28 interacting genes: C4orf46 CD200 DCUN1D5 DNAJC7 FEN1 GRIP1 HDAC1 HUS1B MSH2 MSH3 MSH6 NEIL1 NTAQ1 OGG1 PCNA POLB RAD1 RAD17 RAD9A RAD9B RHNO1 RPA1 RPA2 SDCBP SIRT6 TDG TOPBP1 YWHAQ	5 interacting genes: HUS1 HUS1B RAD1 RAD17 RAD9A
Entrez ID		3364	144715
HPRD ID		04787	12221
Ensembl ID		ENSG00000136273	ENSG00000151164
Uniprot IDs		A4D2F2 O60921	A0A024RBJ5 A0A024RBN9 B4DX60 B4DYM6 J3KPN7 Q6WBX8
PDB IDs		3A1J 3G65 3GGR 6J8Y
Enriched GO Terms of Interacting Partners?
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