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AKT1 and HSP90AA1
Data Source:
BioGRID
(affinity chromatography technology, affinity chromatography technology)
HPRD
(in vivo)
AKT1
HSP90AA1
Description
AKT serine/threonine kinase 1
heat shock protein 90 alpha family class A member 1
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Mitochondrion
Spindle
Cytosol
Plasma Membrane
Cell-cell Junction
Microtubule Cytoskeleton
Lamellipodium
Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
Vesicle
Protein-containing Complex
Ciliary Basal Body
Postsynapse
Extracellular Region
Nucleus
Nucleoplasm
Cytoplasm
Mitochondrion
Cytosol
Plasma Membrane
Membrane
Protein-containing Complex
Secretory Granule Lumen
Melanosome
Neuronal Cell Body
Lysosomal Lumen
Myelin Sheath
Dendritic Growth Cone
Axonal Growth Cone
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Endocytic Vesicle Lumen
Ficolin-1-rich Granule Lumen
Molecular Function
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Protein Serine/threonine/tyrosine Kinase Activity
Protein Kinase C Binding
Protein Binding
Calmodulin Binding
ATP Binding
Phosphatidylinositol-3,4,5-trisphosphate Binding
Kinase Activity
Enzyme Binding
Nitric-oxide Synthase Regulator Activity
GTPase Activating Protein Binding
Identical Protein Binding
Protein Homodimerization Activity
Phosphatidylinositol-3,4-bisphosphate Binding
Protein Phosphatase 2A Binding
14-3-3 Protein Binding
Protein Serine Kinase Activity
Protein Threonine Kinase Activity
RNA Binding
Protein Binding
ATP Binding
ATPase Activity
MHC Class II Protein Complex Binding
Nitric-oxide Synthase Regulator Activity
TPR Domain Binding
Ubiquitin Protein Ligase Binding
Identical Protein Binding
Protein Homodimerization Activity
Histone Deacetylase Binding
Protein Folding Chaperone
Tau Protein Binding
GTPase Binding
Unfolded Protein Binding
DNA Polymerase Binding
Scaffold Protein Binding
Disordered Domain Specific Binding
Protein Tyrosine Kinase Binding
Biological Process
Osteoblast Differentiation
Maternal Placenta Development
Positive Regulation Of Protein Phosphorylation
Positive Regulation Of Endothelial Cell Proliferation
Cell Migration Involved In Sprouting Angiogenesis
Sphingosine-1-phosphate Receptor Signaling Pathway
Glycogen Biosynthetic Process
Regulation Of Glycogen Biosynthetic Process
Glucose Metabolic Process
Translation
Regulation Of Translation
Protein Phosphorylation
Negative Regulation Of Protein Kinase Activity
Protein Import Into Nucleus
Nitric Oxide Biosynthetic Process
Activation-induced Cell Death Of T Cells
Inflammatory Response
Cellular Response To DNA Damage Stimulus
Response To Oxidative Stress
Signal Transduction
Epidermal Growth Factor Receptor Signaling Pathway
G Protein-coupled Receptor Signaling Pathway
I-kappaB Kinase/NF-kappaB Signaling
Germ Cell Development
Aging
Cell Population Proliferation
Positive Regulation Of Cell Population Proliferation
Insulin Receptor Signaling Pathway
Apoptotic Mitochondrial Changes
Carbohydrate Transport
Response To Heat
Negative Regulation Of Autophagy
Positive Regulation Of Endothelial Cell Migration
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Negative Regulation Of Long-chain Fatty Acid Import Across Plasma Membrane
Fibroblast Migration
Positive Regulation Of Fibroblast Migration
Positive Regulation Of Sodium Ion Transport
Positive Regulation Of Glucose Metabolic Process
Positive Regulation Of Mitochondrial Membrane Potential
Negative Regulation Of Endopeptidase Activity
Regulation Of Neuron Projection Development
Phosphatidylinositol 3-kinase Signaling
Negative Regulation Of Macroautophagy
Phosphorylation
Protein Ubiquitination
Peptidyl-serine Phosphorylation
Peptidyl-threonine Phosphorylation
Cytokine-mediated Signaling Pathway
Spinal Cord Development
Cell Projection Organization
Cell Differentiation
Protein Catabolic Process
Hyaluronan Metabolic Process
Positive Regulation Of Cell Growth
Regulation Of Cell Migration
Endocrine Pancreas Development
T Cell Costimulation
Negative Regulation Of Protein Ubiquitination
Regulation Of Myelination
Lipopolysaccharide-mediated Signaling Pathway
TOR Signaling
Negative Regulation Of Fatty Acid Beta-oxidation
Positive Regulation Of Endodeoxyribonuclease Activity
Negative Regulation Of Protein Binding
Response To Food
Activation Of Protein Kinase B Activity
Positive Regulation Of Cellular Protein Metabolic Process
Peripheral Nervous System Myelin Maintenance
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Cellular Response To Insulin Stimulus
Positive Regulation Of Peptidyl-serine Phosphorylation
Response To Fluid Shear Stress
Cellular Response To Reactive Oxygen Species
Intracellular Signal Transduction
Interleukin-18-mediated Signaling Pathway
Cellular Response To Vascular Endothelial Growth Factor Stimulus
NIK/NF-kappaB Signaling
Glucose Homeostasis
Regulation Of Apoptotic Process
Positive Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Anoikis
Regulation Of MRNA Stability
Protein Kinase B Signaling
Positive Regulation Of Blood Vessel Endothelial Cell Migration
Positive Regulation Of Nitric Oxide Biosynthetic Process
Positive Regulation Of Fat Cell Differentiation
Positive Regulation Of Glycogen Biosynthetic Process
Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Negative Regulation Of Notch Signaling Pathway
Negative Regulation Of Cell Size
Negative Regulation Of Proteolysis
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Vasoconstriction
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Glucose Import
Negative Regulation Of JNK Cascade
Positive Regulation Of Organ Growth
Protein Autophosphorylation
Positive Regulation Of Lipid Biosynthetic Process
Insulin-like Growth Factor Receptor Signaling Pathway
Positive Regulation Of Smooth Muscle Cell Proliferation
Regulation Of Nitric-oxide Synthase Activity
Positive Regulation Of Nitric-oxide Synthase Activity
Positive Regulation Of DNA-binding Transcription Factor Activity
Striated Muscle Cell Differentiation
Negative Regulation Of Protein Kinase B Signaling
Excitatory Postsynaptic Potential
Response To Growth Hormone
Mammary Gland Epithelial Cell Differentiation
Labyrinthine Layer Blood Vessel Development
Response To UV-A
Cellular Response To Mechanical Stimulus
Cellular Response To Cadmium Ion
Cellular Response To Tumor Necrosis Factor
Cellular Response To Epidermal Growth Factor Stimulus
Cellular Response To Prostaglandin E Stimulus
Cellular Response To Organic Cyclic Compound
Cellular Response To Hypoxia
Negative Regulation Of Protein Serine/threonine Kinase Activity
Establishment Of Protein Localization To Mitochondrion
Maintenance Of Protein Location In Mitochondrion
Negative Regulation Of Release Of Cytochrome C From Mitochondria
Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus
Execution Phase Of Apoptosis
Negative Regulation Of Protein Kinase Activity By Protein Phosphorylation
Cellular Response To Oxidised Low-density Lipoprotein Particle Stimulus
Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle
Positive Regulation Of Protein Localization To Nucleus
Negative Regulation Of Neuron Death
Regulation Of Signal Transduction By P53 Class Mediator
Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of Leukocyte Cell-cell Adhesion
Positive Regulation Of Protein Localization To Plasma Membrane
Positive Regulation Of I-kappaB Phosphorylation
Cellular Response To Nerve Growth Factor Stimulus
Response To Insulin-like Growth Factor Stimulus
Positive Regulation Of Protein Localization To Cell Surface
Negative Regulation Of Lymphocyte Migration
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
G2/M Transition Of Mitotic Cell Cycle
Positive Regulation Of Protein Phosphorylation
Activation Of Innate Immune Response
Positive Regulation Of Defense Response To Virus By Host
Protein Folding
Mitochondrial Transport
Receptor-mediated Endocytosis
Response To Unfolded Protein
Telomere Maintenance Via Telomerase
Response To Heat
Response To Cold
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Viral Process
Cytokine-mediated Signaling Pathway
Central Nervous System Neuron Axonogenesis
Establishment Of Cell Polarity
Regulation Of Protein Ubiquitination
Positive Regulation Of Protein Polymerization
Positive Regulation Of Interferon-beta Production
Positive Regulation Of Peptidyl-serine Phosphorylation
Cellular Response To Heat
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
ERBB2 Signaling Pathway
Protein Refolding
Regulation Of Apoptotic Process
Regulation Of Protein-containing Complex Assembly
Neutrophil Degranulation
Protein Unfolding
Protein Insertion Into Mitochondrial Outer Membrane
Positive Regulation Of Nitric Oxide Biosynthetic Process
Response To Antibiotic
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Axon Extension
Protein Stabilization
Regulation Of Nitric-oxide Synthase Activity
Chaperone-mediated Protein Complex Assembly
Positive Regulation Of Protein Kinase B Signaling
Positive Regulation Of Telomerase Activity
Chaperone-mediated Autophagy
Ciliary Basal Body-plasma Membrane Docking
Cellular Response To Virus
Regulation Of Cellular Response To Heat
Positive Regulation Of Tau-protein Kinase Activity
Positive Regulation Of Cellular Protein Catabolic Process
Regulation Of Cellular Protein Localization
Telomerase Holoenzyme Complex Assembly
Pathways
Activation of BAD and translocation to mitochondria
PIP3 activates AKT signaling
PIP3 activates AKT signaling
Downregulation of ERBB2:ERBB3 signaling
Translocation of SLC2A4 (GLUT4) to the plasma membrane
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
MTOR signalling
AKT phosphorylates targets in the cytosol
AKT phosphorylates targets in the cytosol
AKT phosphorylates targets in the nucleus
Negative regulation of the PI3K/AKT network
eNOS activation
AKT-mediated inactivation of FOXO1A
Integrin signaling
Deactivation of the beta-catenin transactivating complex
CD28 dependent PI3K/Akt signaling
CTLA4 inhibitory signaling
G beta:gamma signalling through PI3Kgamma
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
KSRP (KHSRP) binds and destabilizes mRNA
VEGFR2 mediated vascular permeability
TP53 Regulates Metabolic Genes
Constitutive Signaling by AKT1 E17K in Cancer
Interleukin-4 and Interleukin-13 signaling
Regulation of TP53 Degradation
Regulation of TP53 Activity through Acetylation
Regulation of TP53 Activity through Association with Co-factors
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
Cyclin E associated events during G1/S transition
Cyclin A:Cdk2-associated events at S phase entry
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1
RAB GEFs exchange GTP for GDP on RABs
RUNX2 regulates genes involved in cell migration
Regulation of PTEN stability and activity
Extra-nuclear estrogen signaling
Negative regulation of NOTCH4 signaling
FLT3 Signaling
Regulation of localization of FOXO transcription factors
Estrogen-dependent nuclear events downstream of ESR-membrane signaling
Signaling by ERBB2
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
vRNP Assembly
Regulation of actin dynamics for phagocytic cup formation
eNOS activation
Regulation of PLK1 Activity at G2/M Transition
Scavenging by Class F Receptors
Scavenging by Class F Receptors
HSP90 chaperone cycle for steroid hormone receptors (SHR)
HSF1 activation
Attenuation phase
HSF1-dependent transactivation
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Sema3A PAK dependent Axon repulsion
VEGFA-VEGFR2 Pathway
VEGFA-VEGFR2 Pathway
VEGFR2 mediated vascular permeability
Uptake and function of diphtheria toxin
PIWI-interacting RNA (piRNA) biogenesis
Anchoring of the basal body to the plasma membrane
Constitutive Signaling by EGFRvIII
Regulation of necroptotic cell death
Interleukin-4 and Interleukin-13 signaling
Neutrophil degranulation
The role of GTSE1 in G2/M progression after G2 checkpoint
AURKA Activation by TPX2
Downregulation of ERBB2 signaling
ESR-mediated signaling
Extra-nuclear estrogen signaling
RHOBTB2 GTPase cycle
Estrogen-dependent gene expression
Chaperone Mediated Autophagy
Constitutive Signaling by Overexpressed ERBB2
Aggrephagy
Drug-mediated inhibition of ERBB2 signaling
Signaling by ERBB2 KD Mutants
Resistance of ERBB2 KD mutants to trastuzumab
Resistance of ERBB2 KD mutants to sapitinib
Resistance of ERBB2 KD mutants to tesevatinib
Resistance of ERBB2 KD mutants to neratinib
Resistance of ERBB2 KD mutants to osimertinib
Resistance of ERBB2 KD mutants to afatinib
Resistance of ERBB2 KD mutants to AEE788
Resistance of ERBB2 KD mutants to lapatinib
Signaling by ERBB2 ECD mutants
Signaling by ERBB2 TMD/JMD mutants
Drug resistance in ERBB2 TMD/JMD mutants
Potential therapeutics for SARS
Drugs
ATP
Arsenic trioxide
Genistein
Inositol 1,3,4,5-Tetrakisphosphate
Resveratrol
Archexin
Enzastaurin
Perifosine
N-[2-(5-methyl-4H-1,2,4-triazol-3-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
5-(5-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine
Rifabutin
Nedocromil
9-Butyl-8-(2,5-Dimethoxy-Benzyl)-9h-Purin-6-Ylamine
Geldanamycin
8-(2-Chloro-3,4,5-Trimethoxy-Benzyl)-2-Fluoro-9-Pent-4-Ylnyl-9h-Purin-6-Ylamine
9-Butyl-8-(3,4,5-Trimethoxybenzyl)-9h-Purin-6-Amine
4-(1,3-Benzodioxol-5-Yl)-5-(5-Ethyl-2,4-Dihydroxyphenyl)-2h-Pyrazole-3-Carboxylic Acid
8-(2,5-Dimethoxy-Benzyl)-2-Fluoro-9h-Purin-6-Ylamine
8-(2,5-Dimethoxy-Benzyl)-2-Fluoro-9-Pent-9h-Purin-6-Ylamine
9-Butyl-8-(2-Chloro-3,4,5-Trimethoxy-Benzyl)-9h-Purin-6-Ylamine
4-(1h-Imidazol-4-Yl)-3-(5-Ethyl-2,4-Dihydroxy-Phenyl)-1h-Pyrazole
9-Butyl-8-(3-Methoxybenzyl)-9h-Purin-6-Amine
9-Butyl-8-(4-Methoxybenzyl)-9h-Purin-6-Amine
9-Butyl-8-(2,5-Dimethoxy-Benzyl)-2-Fluoro-9h-Purin-6-Ylamine
Quercetin
8-Benzo[1,3]Dioxol-,5-Ylmethyl-9-Butyl-2-Fluoro-9h-Purin-6-Ylamine
8-(2-Chloro-3,4,5-Trimethoxy-Benzyl)-9-Pent-4-Ylnyl-9h-Purin-6-Ylamine
N-[4-(AMINOSULFONYL)BENZYL]-5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-1H-PYRAZOLE-4-CARBOXAMIDE
Tanespimycin
SNX-5422
N-(4-ACETYLPHENYL)-5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-1H-PYRAZOLE-4-CARBOXAMIDE
4-CHLORO-6-(4-{4-[4-(METHYLSULFONYL)BENZYL]PIPERAZIN-1-YL}-1H-PYRAZOL-5-YL)BENZENE-1,3-DIOL
5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-PIPERAZIN-1-YL-1H-PYRAZOLE-3-CARBOXAMIDE
5-(5-chloro-2,4-dihydroxyphenyl)-N-ethyl-4-[4-(morpholin-4-ylmethyl)phenyl]isoxazole-3-carboxamide
5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-(4-METHOXYPHENYL)ISOXAZOLE-3-CARBOXAMIDE
2-amino-4-[2,4-dichloro-5-(2-pyrrolidin-1-ylethoxy)phenyl]-N-ethylthieno[2,3-d]pyrimidine-6-carboxamide
4-CHLORO-6-(4-PIPERAZIN-1-YL-1H-PYRAZOL-5-YL)BENZENE-1,3-DIOL
(3E)-3-[(phenylamino)methylidene]dihydrofuran-2(3H)-one
6-(3-BROMO-2-NAPHTHYL)-1,3,5-TRIAZINE-2,4-DIAMINE
3-({2-[(2-AMINO-6-METHYLPYRIMIDIN-4-YL)ETHYNYL]BENZYL}AMINO)-1,3-OXAZOL-2(3H)-ONE
N-[(2-AMINO-6-METHYLPYRIMIDIN-4-YL)METHYL]-3-{[(E)-(2-OXODIHYDROFURAN-3(2H)-YLIDENE)METHYL]AMINO}BENZENESULFONAMIDE
5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-(4-METHOXYPHENYL)-1H-PYRAZOLE-3-CARBOXAMIDE
4-bromo-6-(6-hydroxy-1,2-benzisoxazol-3-yl)benzene-1,3-diol
CCT-018159
4-chloro-6-{5-[(2-morpholin-4-ylethyl)amino]-1,2-benzisoxazol-3-yl}benzene-1,3-diol
8-(6-BROMO-BENZO[1,3]DIOXOL-5-YLSULFANYL)-9-(3-ISOPROPYLAMINO-PROPYL)-ADENINE
4-methyl-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidin-2-amine
(5E,7S)-2-amino-7-(4-fluoro-2-pyridin-3-ylphenyl)-4-methyl-7,8-dihydroquinazolin-5(6H)-one oxime
8-BENZO[1,3]DIOXOL-,5-YLMETHYL-9-BUTYL-9H-
4-{[(2R)-2-(2-methylphenyl)pyrrolidin-1-yl]carbonyl}benzene-1,3-diol
2-(1H-pyrrol-1-ylcarbonyl)benzene-1,3,5-triol
2-[(2-methoxyethyl)amino]-4-(4-oxo-1,2,3,4-tetrahydro-9H-carbazol-9-yl)benzamide
4-(2-methoxyethoxy)-6-methylpyrimidin-2-amine
4-(2,4-dichlorophenyl)-5-phenyldiazenyl-pyrimidin-2-amine
3,6-DIAMINO-5-CYANO-4-(4-ETHOXYPHENYL)THIENO[2,3-B]PYRIDINE-2-CARBOXAMIDE
2-AMINO-4-(2,4-DICHLOROPHENYL)-N-ETHYLTHIENO[2,3-D]PYRIMIDINE-6-CARBOXAMIDE
Copper
Polaprezinc
Alvespimycin
Diseases
PTEN hamartoma tumor syndrome (PHTS), including: Cowden syndrome; Bannayan-Riley-Ruvalcaba syndrome; Proteus syndrome; Proteus-like syndrome
GWAS
Apolipoprotein A1 levels (
32203549
)
Endometrial cancer (
27135401
)
Endometrial endometrioid carcinoma (
27135401
)
HDL cholesterol (
24097068
30275531
25961943
)
HDL cholesterol levels (
32203549
28334899
)
Neutrophil count (
32888494
)
Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) (
30940143
)
Interacting Genes
319 interacting genes:
ACAP1
ACAT2
AGAP2
AGR3
AHNAK
AHSA1
AKT1S1
AKT2
AKTIP
ALYREF
APLP2
APOH
APP
APPL1
AR
ARAF
ARFIP2
ARNT
ATXN1
AURKA
BABAM1
BAD
BCL10
BCL2L1
BCL2L11
BCL3
BECN1
BEX1
BLVRA
BPGM
BRAF
BRCA1
BUB1
CAMKK1
CARHSP1
CASC3
CASP3
CASP9
CBLC
CCDC88A
CCND2
CCNE1
CCNF
CCNI
CD44
CDC37
CDH1
CDK4
CDK6
CDKN1A
CDKN1B
CDKN1C
CDKN2A
CDKN2B
CDKN2C
CEP57L1
CEP76
CHEK1
CHUK
CLASP2
CLIP3
CLK2
CNOT9
CREB1
CREBBP
CSNK2A1
CTDSP2
CTNNA1
CTNNB1
CYLD
DAB2IP
DCTN1
DDIT4L
DLC1
DNAJB1
DNMT1
EEF1G
EIF4EBP1
EMSY
ENO2
EP300
EPHA2
EPSTI1
ERBB2
ESR1
ESR2
EZH2
FAF1
FANCA
FANCI
FASN
FBXO31
FBXW7
FGFR4
FOXO1
FOXO3
FOXO4
FUS
FZR1
GAB2
GATA1
GATA2
GET4
GFAP
GJA1
GLIS2
GRB10
GRIN2A
GSK3A
GSK3B
H2BC21
H2BC3
HIF1A
HMOX1
HSP90AA1
HSP90AB1
HSPB1
HTT
IKBKB
IL13RA2
IL24
ILK
IMPDH2
IRAK1
IRS1
ITGB3
ITPR1
ITPR3
IWS1
JADE1
KANK1
KAT2A
KAT2B
KAT6A
KDELR2
KLHL3
KMT2D
KRT10
LANCL2
LATS2
LRRK2
LTB4R2
MAP2K3
MAP2K4
MAP2K5
MAP2K6
MAP3K11
MAP3K5
MAP3K8
MAPK14
MAPK8
MAPK8IP1
MAPK9
MAPKAP1
MAPKAPK2
MAPT
MATK
MDM2
MDM4
MESD
METTL1
MLH3
MRC2
MS4A2
MSH2
MST1R
MTA3
MTCP1
MTOR
MTUS2
MUL1
MXD1
MYC
NCF2
NCOA4
NCOR2
NF1
NF2
NGB
NOL4
NOS3
NOTCH1
NR4A1
NRAS
NSD3
OSGIN1
PAK1
PDE3A
PDE3B
PDGFRA
PDHB
PDK1
PDK2
PDPK1
PEA15
PFKFB1
PFKFB2
PFKP
PHB2
PI4K2B
PIAS1
PIAS2
PICK1
PIK3CA
PIK3R1
PIP5K1C
PKN2
PLCG1
PLEKHO1
PLP1
PLXNA1
PMS2
PPARGC1B
PPL
PPM1A
PPP2CA
PPP2R1A
PRG2
PRKCQ
PRKCZ
PRKDC
PSMC5
PTEN
PTGDS
PTPA
PTPN1
PTPN11
PTPN3
PYGO2
RAB3D
RAC1
RAF1
RARA
RASL10B
RASSF1
RGCC
RHEBL1
RNF11
RNF115
RPS6KB1
S100A14
S1PR1
SERPINB5
SETDB1
SH2B2
SH3RF1
SIRPA
SIRT1
SIRT6
SKI
SKP2
SLC9A3R1
SMAD2
SMAD3
SMAD4
SMAD7
SMARCB1
SMARCC1
SNCA
SNCB
SORBS2
SOX2
SOX4
SP1
SP3
SRC
SRPK2
SRR
SSH1
ST14
STAT1
STK11
STK3
STK4
SULT4A1
SUPT6H
SYTL1
TBC1D4
TBC1D7
TCL1A
TCL1B
TCL6
TEAD2
TERF2IP
TERT
TFF1
THEM4
THRSP
TLR2
TMCC2
TNFRSF1A
TNFSF11
TNK2
TOPBP1
TP53
TRIB3
TRIM13
TRMT2B
TSC1
TSC2
TTC3
UBE2S
UCHL1
USP4
UXS1
VEGFA
VHL
VIM
WNK1
WNK4
XAF1
XIAP
YAP1
YBX1
YWHAZ
ZFP36L1
ZHX1
ZNF691
ZRANB1
158 interacting genes:
AHR
AHSA1
AHSA2P
AIP
AIPL1
AKT1
AKT2
APAF1
APOB
AR
ARNTL
ASGR1
BIRC5
BRMS1
CACYBP
CALM1
CDC37
CDC37L1
CDK4
CDK5R1
CDKN2A
CERS2
CFTR
CHEK1
CHORDC1
CHUK
CKS1B
CKS2
CRNKL1
CSNK2A1
CSNK2A2
DAP3
DNAJC7
EGFR
EGLN1
EIF2AK1
EIF2AK2
EIF2AK3
EIF2S1
EPAS1
EPRS1
ERBB2
ERN1
ESR1
ESRRB
FAM162A
FANCA
FANCC
FKBP1A
FKBP4
FKBP5
FKBP6
FLCN
FNIP1
FYN
GABARAPL1
GNA12
GSK3B
GUCY1B1
GZMA
HDAC6
HIF1A
HIF3A
HSF1
HSPA8
HTT
IKBKB
IKBKE
IKBKG
IP6K2
IRAK1
IRF3
ITGB1BP2
JUN
KDR
KEAP1
LCK
LINC01554
LSM1
MAP3K14
MAP3K3
MAPK1
MAPT
MIS12
MMP2
MS4A2
MTRNR2L1
MUC1
MYC
MYOD1
NDRG1
NOS1
NOS3
NPAS2
NR2C2
NR3C1
NR3C2
NSL1
PABPN1
PAK1
PDPK1
PIM1
PMF1
PPARA
PPARD
PPID
PPIL2
PPP5C
PRKACA
PRKCA
PRKCD
PRKDC
PTGDS
PTGES3
PTPRF
RAD51
RAF1
RHOBTB2
RIPK1
RPAP3
RPS3
RPS3A
RUNX1T1
SERPINB5
SGTA
SIM1
SKP1
SLC2A4
SLC34A1
SMYD2
SMYD3
SNCA
SRC
ST13
STARD13
STAT3
STIP1
STUB1
SUGT1
SUMO2
SVIL
TBK1
TERT
TJP1
TNFRSF1A
TOMM34
TOMM40
TOMM70
TP53
TTK
TTR
UBASH3A
UBE2N
UCHL1
UNC45A
USP19
USP50
WASL
Entrez ID
207
3320
HPRD ID
01261
00777
Ensembl ID
ENSG00000142208
ENSG00000080824
Uniprot IDs
B0LPE5
B3KVH4
P31749
K9JA46
P07900
Q86SX1
PDB IDs
1H10
1UNP
1UNQ
1UNR
2UVM
2UZR
2UZS
3CQU
3CQW
3MV5
3MVH
3O96
3OCB
3OW4
3QKK
3QKL
3QKM
4EJN
4EKK
4EKL
4GV1
5KCV
6BUU
6CCY
6HHF
6HHG
6HHH
6HHI
6HHJ
6NPZ
6S9W
6S9X
1BYQ
1OSF
1UY6
1UY7
1UY8
1UY9
1UYC
1UYD
1UYE
1UYF
1UYG
1UYH
1UYI
1UYK
1UYL
1YC1
1YC3
1YC4
1YER
1YES
1YET
2BSM
2BT0
2BUG
2BYH
2BYI
2BZ5
2C2L
2CCS
2CCT
2CCU
2FWY
2FWZ
2H55
2JJC
2K5B
2QF6
2QFO
2QG0
2QG2
2UWD
2VCI
2VCJ
2WI1
2WI2
2WI3
2WI4
2WI5
2WI6
2WI7
2XAB
2XDK
2XDL
2XDS
2XDU
2XDX
2XHR
2XHT
2XHX
2XJG
2XJJ
2XJX
2XK2
2YE2
2YE3
2YE4
2YE5
2YE6
2YE7
2YE8
2YE9
2YEA
2YEB
2YEC
2YED
2YEE
2YEF
2YEG
2YEH
2YEI
2YEJ
2YI0
2YI5
2YI6
2YI7
2YJW
2YJX
2YK2
2YK9
2YKB
2YKC
2YKE
2YKI
2YKJ
3B24
3B25
3B26
3B27
3B28
3BM9
3BMY
3D0B
3EKO
3EKR
3FT5
3FT8
3HEK
3HHU
3HYY
3HYZ
3HZ1
3HZ5
3INW
3INX
3K97
3K98
3K99
3MNR
3O0I
3OW6
3OWB
3OWD
3Q6M
3Q6N
3QDD
3QTF
3R4M
3R4N
3R4O
3R4P
3R91
3R92
3RKZ
3RLP
3RLQ
3RLR
3T0H
3T0Z
3T10
3T1K
3T2S
3TUH
3VHA
3VHC
3VHD
3WHA
3WQ9
4AIF
4AWO
4AWP
4AWQ
4B7P
4BQG
4BQJ
4CGQ
4CGU
4CGV
4CGW
4CWF
4CWN
4CWO
4CWP
4CWQ
4CWR
4CWS
4CWT
4EEH
4EFT
4EFU
4EGH
4EGI
4EGK
4FCP
4FCQ
4FCR
4HY6
4JQL
4L8Z
4L90
4L91
4L93
4L94
4LWE
4LWF
4LWG
4LWH
4LWI
4NH7
4NH8
4O04
4O05
4O07
4O09
4O0B
4R3M
4U93
4W7T
4XIP
4XIQ
4XIR
4XIT
4YKQ
4YKR
4YKT
4YKU
4YKW
4YKX
4YKY
4YKZ
5CF0
5FNC
5FND
5FNF
5GGZ
5J20
5J27
5J2V
5J2X
5J64
5J6L
5J6M
5J6N
5J80
5J82
5J86
5J8M
5J8U
5J9X
5LNY
5LNZ
5LO0
5LO1
5LO5
5LO6
5LQ9
5LR1
5LR7
5LRL
5LRZ
5LS1
5M4E
5M4H
5NYH
5NYI
5OCI
5OD7
5ODX
5T21
5VYY
5XQD
5XQE
5XR5
5XR9
5XRB
5XRD
5XRE
5ZR3
6B99
6B9A
6CEO
6CYG
6CYH
6EI5
6EL5
6ELN
6ELO
6ELP
6EY8
6EY9
6EYA
6EYB
6F1N
6FCJ
6FDP
6GP4
6GP8
6GPF
6GPH
6GPO
6GPP
6GPR
6GPT
6GPW
6GPY
6GQ6
6GQR
6GQS
6GQU
6GR1
6GR3
6GR4
6GR5
6HHR
6KSQ
6N8X
6OLX
6TN4
6TN5
6U98
6U99
6U9A
6U9B
Enriched GO Terms of Interacting Partners
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