ZBTB25 and TBC1D5

Data Source:
BioGRID (two hybrid)

		ZBTB25	TBC1D5
Description		zinc finger and BTB domain containing 25	TBC1 domain family member 5
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm	Autophagosome Golgi Apparatus Cytosol Endosome Membrane AP-2 Adaptor Complex Retromer Complex Intracellular Membrane-bounded Organelle Atg1/ULK1 Kinase Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding	GTPase Activator Activity Protein Binding AP-2 Adaptor Complex Binding Protein-containing Complex Binding Retromer Complex Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II	Positive Regulation Of Receptor Internalization Intracellular Protein Transport Autophagy Macroautophagy Retrograde Transport, Endosome To Golgi Response To Starvation Activation Of GTPase Activity Regulation Of Cilium Assembly
Pathways
Drugs
Diseases
GWAS		Heel bone mineral density ( 30598549) Lymphocyte counts ( 27863252) Lymphocyte percentage of white cells ( 32888494 27863252)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) General risk tolerance (MTAG) ( 30643258) Height ( 28552196) Mean platelet volume ( 32888494 27863252) Midgestational circulating levels of PBDEs (fetal genetic effect) ( 28235828) Parkinson's disease ( 32201043) Platelet count ( 32888494 27863252) Platelet distribution width ( 27863252) Plateletcrit ( 32888494 27863252) Schizophrenia ( 28991256 25056061 29483656) Self-reported risk-taking behaviour ( 30271922) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		34 interacting genes: APIP COIL CRACR2B CYP2J2 CYSRT1 DDIT3 FCGR3A FHL2 HCLS1 HOMEZ HSBP1 KCTD1 KCTD9 KRTAP10-8 KRTAP17-1 KXD1 LZTS2 MAPK9 MDFI PCBD1 PNMA5 SEPHS1 SORBS3 SSX3 SUMO2 TBC1D5 TNIP1 TRAF2 TRAF6 TSSK3 VCP VMAC ZBTB1 ZBTB2	10 interacting genes: AP2M1 ATXN1 CHIA EIF1AD FBXL7 GABARAPL1 GABARAPL2 MAP1LC3A UBC ZBTB25
Entrez ID		7597	9779
HPRD ID		01926	10262
Ensembl ID		ENSG00000089775	ENSG00000131374
Uniprot IDs		G3V2K3 P24278	B9A6K1 Q92609
PDB IDs			5GTU
Enriched GO Terms of Interacting Partners?
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