HPCAL1 and MYDGF

Data Source:
BioGRID (two hybrid)

		HPCAL1	MYDGF
Description		hippocalcin like 1	myeloid derived growth factor
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GO Annotations	Cellular Component	Membrane	Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus
	Molecular Function	Calcium Ion Binding Protein Binding	Protein Binding
	Biological Process		Angiogenesis Positive Regulation Of Protein Phosphorylation Positive Regulation Of Endothelial Cell Proliferation Apoptotic Process Positive Regulation Of Phosphatidylinositol 3-kinase Signaling IRE1-mediated Unfolded Protein Response Negative Regulation Of Apoptotic Process Positive Regulation Of MAPK Cascade Positive Regulation Of Angiogenesis Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Protein Kinase B Signaling
Pathways			XBP1(S) activates chaperone genes
Drugs
Diseases
GWAS		Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) Kidney function decline traits ( 25493955) Lung function (FEV1/FVC) ( 30061609) Platelet distribution width ( 32888494)
Interacting Genes		38 interacting genes: AMOT ATXN1 C19orf44 C1QTNF2 CA3 COLGALT2 CREM DTX2 EFEMP2 EPHB3 FZD7 GATA5 HMG20A IKBKG KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP17-1 KRTAP4-2 KRTAP5-9 LITAF MDFI MICOS10-NBL1 MYDGF NBL1 NBPF19 NOTCH2NLA PLAAT2 SERPINI2 SLC34A1 TPSG1 VWC2 ZNF655	13 interacting genes: ACOT13 BAG6 EIF3F HPCA HPCAL1 LCN2 MDM2 NCALD SGTA SGTB UBQLN1 UBQLN2 UBQLN4
Entrez ID		3241	56005
HPRD ID		02564	08415
Ensembl ID		ENSG00000115756	ENSG00000074842
Uniprot IDs		O75544 P37235 Q6FGY1	Q969H8
PDB IDs		5T7C	6O6W 6SVK 6SVL
Enriched GO Terms of Interacting Partners?
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