MYDGF and ACOT13

Data Source:
BioGRID (two hybrid)

		MYDGF	ACOT13
Description		myeloid derived growth factor	acyl-CoA thioesterase 13
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GO Annotations	Cellular Component	Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus	Nucleus Mitochondrion Spindle Cytosol
	Molecular Function	Protein Binding	Protein Binding Palmitoyl-CoA Hydrolase Activity Metal Ion Binding Acyl-CoA Hydrolase Activity Myristoyl-CoA Hydrolase Activity
	Biological Process	Angiogenesis Positive Regulation Of Protein Phosphorylation Positive Regulation Of Endothelial Cell Proliferation Apoptotic Process Positive Regulation Of Phosphatidylinositol 3-kinase Signaling IRE1-mediated Unfolded Protein Response Negative Regulation Of Apoptotic Process Positive Regulation Of MAPK Cascade Positive Regulation Of Angiogenesis Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Protein Kinase B Signaling	Acyl-CoA Metabolic Process Protein Homotetramerization Negative Regulation Of Cold-induced Thermogenesis
Pathways		XBP1(S) activates chaperone genes	Mitochondrial Fatty Acid Beta-Oxidation
Drugs			2-Undecanone
Diseases
GWAS			Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444)
Interacting Genes		13 interacting genes: ACOT13 BAG6 EIF3F HPCA HPCAL1 LCN2 MDM2 NCALD SGTA SGTB UBQLN1 UBQLN2 UBQLN4	4 interacting genes: MYDGF NTAQ1 RBBP6 SPG21
Entrez ID		56005	55856
HPRD ID		08415	07158
Ensembl ID		ENSG00000074842	ENSG00000112304
Uniprot IDs		Q969H8	Q9NPJ3
PDB IDs		6O6W 6SVK 6SVL	2F0X 2H4U 3F5O
Enriched GO Terms of Interacting Partners?
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