APC and KIF5B

  • Data Source:
  • BioGRID (two hybrid)

APC

KIF5B

Description APC regulator of WNT signaling pathway kinesin family member 5B
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Angiotensin-converting enzyme inhibitor intolerance ( 28030426)
  • Body mass index ( 29273807)
  • Colorectal cancer or advanced adenoma ( 30510241)
  • Heel bone mineral density ( 30598549)
  • Reaction time ( 29844566)
  • Total body bone mineral density ( 29304378)
  • Anti-saccade response ( 29064472)
  • Bipolar disorder with mood-incongruent psychosis ( 23092984)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Glycine levels ( 30837465)
  • Pulse pressure ( 27841878)
  • Systolic blood pressure ( 27841878)
  • Waist-to-hip ratio adjusted for BMI ( 26426971)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes 138 interacting genes: ACTN1 ADGRL1 AGFG1 AGR3 ANKRD17 ANP32B ANXA7 AP2B1 ARHGEF4 ASAP2 AXIN1 AXIN2 BAAT BUB1 BUB1B C4A CASC3 CCL5 CGNL1 COG4 COG5 CREBBP CSNK1A1 CSNK1E CTBP1 CTNNA1 CTNNB1 CTSV CYP17A1 CYTH2 DIRAS3 DKK3 DLG3 DLGAP1 DST EPAS1 ERBIN EXPH5 FAM214A FANCC FBP1 FBXO30 FHOD1 FLNA GIGYF2 GOLGA2 GSK3B HGS HNRNPM HOXC6 HSPA5 HTRA2 IL24 ING5 IQGAP1 JUP KIAA1328 KIF5B KIFAP3 KRT13 KRT14 KRT15 KRT17 KRT19 KRT23 KRT5 LAMA3 LAMA4 MACF1 MAP2K1 MAPRE1 MAPRE2 MBD5 MCM3AP MKRN1 MT-ND4 MUC1 MYH10 MYH11 MYO6 NANS NAT2 NAV1 NAV2 NAV3 NCKAP5 NCKAP5L NEB NOSTRIN NUP153 NUP214 NUP42 NUP54 NUP58 NUP98 PDLIM2 PNISR POM121 POM121C PPP1R13B PPP2CA PPP2R5A PPP3R2 PRKACA PSMD1 PTPN13 RANBP9 RASA1 RBM4B RP1 RPS27 SCRIB SEC31A SETDB1 SIAH1 SMAD1 SMC3 SNRNP200 SPECC1L SPTBN1 SPTBN2 ST14 SYNE1 TAF1 TFAP2A TFF1 TGFB1 TMEFF1 TMOD1 TPR TRIM21 TRIM25 TSTD2 TUBA4A XPO1 YWHAQ ZNF106 ZNF510 36 interacting genes: APC BAG4 CCDC136 CDC5L CDR2 DTNB FHL2 GCC1 GSK3B HSF2BP KIF5A KLC3 KTN1 LBX1 MEOX2 MYO5A NCOA2 NDRG1 POLR2G POU6F2 PRKAR1B PRKAR2B RAPGEF2 RRBP1 SNAP23 SNAP25 SUMO2 SYBU TAX1BP1 VPS52 YWHAB YWHAG YWHAH YWHAQ YWHAZ ZBTB8A
Entrez ID 324 3799
HPRD ID 01439 07214
Ensembl ID ENSG00000134982 ENSG00000170759
Uniprot IDs P25054 Q4LE70 P33176 Q6P164 V9HW29
PDB IDs 1DEB 1EMU 1JPP 1M5I 1T08 1TH1 1V18 2RQU 3AU3 3NMW 3NMX 3NMZ 3QHE 3RL7 3RL8 3T7U 4G69 4YJE 4YJL 4YK6 5B6G 5IZ6 5IZ8 5IZ9 5IZA 5Z8H 1BG2 1MKJ 2P4N 3J8X 3J8Y 4HNA 4LNU 5LT0 5LT1 5LT2 5LT3 5LT4 6OJQ
Enriched GO Terms of Interacting Partners?
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